When encephalitogenic T cells collaborate with microglia in multiple sclerosis

Y Dong, VW Yong - Nature Reviews Neurology, 2019 - nature.com
Immune cells mediate critical inflammatory and neurodegenerative processes in the CNS in
individuals with multiple sclerosis (MS). In MS, activated microglia, border-associated …

Re-examining the role of TNF in MS pathogenesis and therapy

D Fresegna, S Bullitta, A Musella, FR Rizzo, F De Vito… - Cells, 2020 - mdpi.com
Multiple sclerosis (MS) is a common neurological disorder of putative autoimmune origin.
Clinical and experimental studies delineate abnormal expression of specific cytokines over …

Inflammation in neurological disorders: the thin boundary between brain and periphery

C Cervellati, A Trentini, A Pecorelli… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Accumulating evidence suggests that inflammation is a major contributor in the
pathogenesis of several highly prevalent, but also rare, neurological diseases. In particular …

Bridging the Gap” Everything that Could Have Been Avoided If We Had Applied Gender Medicine, Pharmacogenetics and Personalized Medicine in the Gender …

D Gemmati, K Varani, B Bramanti, R Piva… - International journal of …, 2019 - mdpi.com
Gender medicine is the first step of personalized medicine and patient-centred care, an
essential development to achieve the standard goal of a holistic approach to patients and …

Extrinsic immune cell-derived, but not intrinsic oligodendroglial factors contribute to oligodendroglial differentiation block in multiple sclerosis

L Starost, M Lindner, M Herold, YKT Xu… - Acta …, 2020 - Springer
Multiple sclerosis (MS) is the most frequent demyelinating disease in young adults and
despite significant advances in immunotherapy, disease progression still cannot be …

Differential contribution of microglia and monocytes in neurodegenerative diseases

C Baufeld, E O'Loughlin, N Calcagno… - Journal of neural …, 2018 - Springer
Neuroinflammation is a hallmark of neurodegenerative diseases including Alzheimer's
disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). Microglia …

Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis

A Sánchez-Fernández, S Zandee… - Journal of …, 2022 - Springer
Background Resolution of inflammation is an active and regulated process that leads to the
clearance of cell debris and immune cells from the challenged tissue, facilitating the …

[HTML][HTML] Correlation of IL-17 level in synovia and severity of knee osteoarthritis

Y Liu, H Peng, Z Meng, M Wei - Medical science monitor …, 2015 - ncbi.nlm.nih.gov
Correlation of IL-17 Level in Synovia and Severity of Knee Osteoarthritis - PMC Back to Top
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Autoreactive lymphocytes in multiple sclerosis: Pathogenesis and treatment target

R Liu, S Du, L Zhao, S Jain, K Sahay… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) characterized by destruction of the myelin sheath structure. The loss of myelin leads …

Pharmacological inhibition of the NLRP3 inflammasome as a potential target for multiple sclerosis induced central neuropathic pain

N Khan, A Kuo, DA Brockman, MA Cooper… - …, 2018 - Springer
The NOD-like receptor (NLR) family pyrin domain-containing protein 3 (NLRP3)
inflammasome is implicated in the pathogenesis of multiple diseases including …