[HTML][HTML] Drug resistance in animal trypanosomiases: Epidemiology, mechanisms and control strategies

MA Ungogo, HP de Koning - … Journal for Parasitology: Drugs and Drug …, 2024 - Elsevier
Animal trypanosomiasis (AT) is a complex of veterinary diseases known under various
names such as nagana, surra, dourine and mal de caderas, depending on the country, the …

[PDF][PDF] Anti-trypanosomal effects of Azadiracta indica (neem) extract on Trypanosoma brucei rhodesiense-infected mice

RM Ngure, B Ongeri, SM Karori… - Eastern Journal of …, 2009 - jag.journalagent.com
An in vivo study was carried out to determine the anti-typanosomal effect of aqueous extracts
of the bark of Azadiracta indica (neem) in Trypanosoma brucei rhodesiense-infected mice …

[HTML][HTML] Senna occidentalis leaf extract possesses antitrypanosomal activity and ameliorates the trypanosome-induced anemia and organ damage

MA Ibrahim, AB Aliyu, AB Sallau, M Bashir… - Pharmacognosy …, 2010 - ncbi.nlm.nih.gov
The in vitro and in vivo antitrypanosomal effects of the ethanol extract of Senna occidentalis
leaf were investigated. The crude extract exhibited an in vitro activity against Trypanosoma …

Antioxidant therapy against trypanosome infections: a review update

M Auwal Ibrahim, M Bindawa Isah… - Current Topics in …, 2016 - ingentaconnect.com
Trypanosomiasis is a serious parasitic disease that affects humans and animals resulting in
heavy health and economic burdens. Disturbance of redox equilibrium represents a …

Phenolics-rich fraction of Khaya senegalensis stem bark: Antitrypanosomal activity and amelioration of some parasite-induced pathological changes

MA Ibrahim, AM Musa, AB Aliyu, HS Mayaki… - Pharmaceutical …, 2013 - Taylor & Francis
Context: The stem bark of Khaya senegalensis A. Juss (Meliaceae) is currently used for the
treatment of trypanosomiasis by traditional practitioners in Nigeria. Objectives: The present …

Effects of aqueous extract of fruit pulp of Adansonia digitata L. on the oxidative stress profile against Trypanosoma brucei brucei infection in albino rats

OO Ogunleye, ID Jatau, AJ Natala… - Clinical …, 2020 - Springer
Background Chemotherapy is the most widely used means of controlling trypanosomosis,
however, effectiveness of the drugs available is limited by a number of factors. This study …

[PDF][PDF] Haematological changes in Trypanosoma brucei brucei infected wistar rats treated with a flavonoid mixture and/or diminazene aceturate

PI Kobo, JO Ayo, T Aluwong, AU Zezi, VA Maikai - Biol Med, 2014 - academia.edu
The aim of the study was to evaluate the effect of treatment with DAFLON® 500 mg (DF)
and/or diminazene aceturate (DZ) on hematological parameters in rats, infected with …

Lactone-rich fraction from Vernonia blumeoides: antitrypanosomal activity and alleviation of the parasite-induced anemia and organ damage

MA Ibrahim, AB Aliyu, H Abdullahi, T Solomon… - Journal of natural …, 2013 - Springer
The anti-Trypanosoma brucei brucei activity in vitro and in vivo of a lactone-rich fraction of
Vernonia blumeoides leaves (VBLF) and its potential in alleviating trypanosome-induced …

Comprehensive analysis of oral administration of Vitamin E on the early stage of Trypanosoma brucei brucei infection

RJ Ojo, GA Enoch, FS Adeh, LC Fompun… - Journal of Parasitic …, 2021 - Springer
Reinforcement of the body with exogenous antioxidants have been shown to mitigate the
negative effects of African trypanosomiasis on the host and contribute greatly to their …

Antitrypanosomal potentials of the extract and fractions of Abrus precatorius seeds

NJ Nwodo, OFC Nwodo - Asian Pacific Journal of Tropical Medicine, 2012 - Elsevier
OBJECTIVE: To evaluate the in vivo trypanocidal activity of the methanol extract and
fractions of Abrus precatorius seeds in mice. METHODS: Parasiteamia was induced unto …