There has been a significant progress in our understanding of the molecular mechanisms by
which calcium (Ca2+) ions mediate various types of cardiac arrhythmias. A growing list of …

In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …

Abstract α-synuclein (αS) is a protein involved in neurotransmitter release in presynaptic
terminals, and whose aberrant aggregation is associated with Parkinson's disease. In …

The calcium pump (aka Ca 2+-ATPase or SERCA) is a membrane transport protein
ubiquitously found in the endoplasmic reticulum (ER) of all eukaryotic cells. As a calcium …

Membrane proteins perform a host of vital cellular functions. Deciphering the molecular
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …

There is an intimate relationship between the thyroid gland and the heart. Thyroid
dysfunction, including subclinical thyroid disease, has significant effects on cardiovascular …

Solid-state nuclear magnetic resonance (ssNMR) spectroscopy enables the structural
characterization of a diverse array of biological assemblies that include amyloid fibrils, non …

P-type ATPases are found in all kingdoms of life and constitute a wide range of cation
transporters, primarily for H+, Na+, K+, Ca2+, and transition metal ions such as Cu (I), Zn (II) …

Membrane-protein NMR occupies a unique niche for determining structures, assessing
dynamics, examining folding, and studying the binding of lipids, ligands and drugs to …

The aggregation of α-synuclein (αS), a protein abundant at presynaptic terminals, is
associated with a range of highly debilitating neurodegenerative conditions, including …