The recent outbreak of the corona virus disease (COVID-19) has had major global impact.
The relationship between severe acute respiratory syndrome coronavirus (SARS-CoV-2) …

Increasing evidence underlines that prototypical inflammatory cytokines (IL-1β, TNF-α and IL-
6) either synthesized in the central (CNS) or peripheral nervous system (PNS) by resident …

Clinical studies indicate that cannabidiol (CBD), the primary nonaddictive component of
cannabis that interacts with the serotonin (5-HT) 1A receptor, may possess analgesic and …

Depression and anxiety disorders are the two most prevalent psychiatric diseases that affect
hundreds of millions of individuals worldwide. Understanding the etiology and related …

Exposure to stress is an undeniable, but in most cases surmountable, part of life. However,
in certain individuals, exposure to severe or cumulative stressors can lead to an array of …

Mood disorders such as depression and anxiety are frequently observed in patients
suffering from chronic pain. Over time, different tests and models have been developed in …

A large set of inflammatory molecules and their receptors are induced in epileptogenic foci
of patients with pharmacoresistant epilepsies of structural etiologies or with refractory status …

Acute pain induces depressed mood, and chronic pain is known to cause depression.
Depression, meanwhile, can also adversely affect pain behaviors ranging from …

The amygdala is a structure of the temporal lobe thought to be involved in assigning
emotional significance to environmental information and triggering adapted physiological …

Sepsis is a prevalent health issue that can lead to central nervous system (CNS)
inflammation with long-term behavioral and cognitive alterations. Using unbiased proteomic …