A comprehensive review of viral characteristics, transmission, pathophysiology, immune response, and management of SARS-CoV-2 and COVID-19 as a basis for …

CR Triggle, D Bansal, H Ding, MM Islam… - Frontiers in …, 2021 - frontiersin.org
COVID-19 emerged from China in December 2019 and during 2020 spread to every
continent including Antarctica. The coronavirus, SARS-CoV-2, has been identified as the …

Incomplete immune reconstitution in HIV/AIDS patients on antiretroviral therapy: Challenges of immunological non-responders

X Yang, B Su, X Zhang, Y Liu, H Wu… - Journal of leukocyte …, 2020 - academic.oup.com
The morbidity and mortality of HIV type-1 (HIV-1)-related diseases were dramatically
diminished by the grounds of the introduction of potent antiretroviral therapy, which induces …

[PDF][PDF] Implications of CD4/CD8 ratios in Human Immunodeficiency Virus infections

EI Obeagu, GY Scott, F Amekpor… - Int. J. Curr. Res. Med …, 2023 - researchgate.net
Abstract Human Immunodeficiency Virus (HIV) is a major Public Health burden to the world
despite all efforts to eradicate the menace. HIV infection is characterized by profound CD4 T …

[HTML][HTML] Utilization of immunological ratios in HIV: Implications for monitoring and therapeutic strategies

EI Obeagu, GU Obeagu - Medicine, 2024 - journals.lww.com
Human immunodeficiency virus (HIV) infection remains a significant global health concern,
necessitating ongoing research and innovation in the quest for improved disease …

[HTML][HTML] CXCL13-CXCR5 axis: Regulation in inflammatory diseases and cancer

B Wang, M Wang, D Ao, X Wei - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Chemokine CXC motif ligand 13 (CXCL13), originally identified as a B-cell chemokine, plays
an important role in the immune system. The interaction between CXCL13 and its receptor …

Sepsis and immunosenescence in the elderly patient: a review

S Martín, A Pérez, C Aldecoa - Frontiers in medicine, 2017 - frontiersin.org
Sepsis is a prevalent, serious medical condition with substantial mortality and a significant
consumption of health-care resources. Its incidence has increased around 9% annually in …

Association between gut microbiota and CD4 recovery in HIV-1 infected patients

W Lu, Y Feng, F Jing, Y Han, N Lyu, F Liu, J Li… - Frontiers in …, 2018 - frontiersin.org
Composition of the gut microbiota has been linked with human immunedeficiency virus (HIV)-
infected patients on antiretroviral therapy (ART). Evidence suggests that ART-treated …

Postacute sequelae and adaptive immune responses in people with HIV recovering from SARS-COV-2 infection

MJ Peluso, MA Spinelli, TM Deveau, CA Forman… - Aids, 2022 - journals.lww.com
Background: Limited data are available on the long-term clinical and immunologic
consequences of SARS-CoV-2 infection in people with HIV (PWH). Methods: We measured …

Effects of vitamin B6 deficiency on the composition and functional potential of T cell populations

B Qian, S Shen, J Zhang, P Jing - Journal of immunology …, 2017 - Wiley Online Library
The immune system is critical in preventing infection and cancer, and malnutrition can
weaken different aspects of the immune system to undermine immunity. Previous studies …

CD4: CD8 ratio and CD8 count as prognostic markers for mortality in human immunodeficiency virus–infected patients on antiretroviral therapy: the Antiretroviral …

A Trickey, MT May, P Schommers, J Tate… - Clinical Infectious …, 2017 - academic.oup.com
Background We investigated whether CD4: CD8 ratio and CD8 count were prognostic for all-
cause, AIDS, and non-AIDS mortality in virologically suppressed patients with high CD4 …