The oxazolidinones are a new and potent class of antimicrobial agents with activity mainly
against Gram-positive strains. The commercial success of linezolid, the only FDA-approved …

Oxazolidinones represent a significant class of synthetic bacterial protein synthesis
inhibitors that are primarily effective against Gram-positive bacteria. The commercial …

In the search for new biologically active molecules, diversity-oriented synthetic strategies
break through the limitation of traditional library synthesis by sampling new chemical space …

Due to the emergence of resistance to known antibiotics to various organisms, for example,
Staphylococcus, Streptococcus, Enterococci, and Pseudomonas there is a renewed interest …

A series of novel rutaecarpine derivatives and related alkaloid derivatives 3-
aminoalkanamido-substituted rutaecarpine 4a–f and 7, 8-dehydrorutaecarpine 5a–c, and 6 …

A series of 3-amino-substituted rutacecarpine derivatives were synthesized to identify novel
multitarget-directed ligands (MTDLs) for the treatment of Alzheimer's disease (AD) …

The Oxazolidinones are a promising novel chemical synthetic class of antibiotics identified
in the last two decades and have been subjected to intensive discovery efforts. They …

A new method to obtain enantiopure 5-substituted 1, 3-oxazolidin-2-ones 1 from
αdibenzylamino esters 2 is reported. This methodology is based on the Lewis acid catalyzed …

Tröger's base is a building block with a unique rigidity and geometry that has an increasing
number of applications in a variety of nanoscale chemistry projects. This paper describes the …

以K 红酸肝为起始原料, 经硝化, 还原上保护, 氨解开环, 环合, 卤素交换和脱保护共L
步反应合成了氟唾酮(M), 其结构经$ C? BD, $ A/? BD 和F: E@ B: 确证. 研究了硝化试剂, 溶剂 …