Methamphetamine abuse disturbs the dopaminergic system to impair hippocampal-based learning and memory: An overview of animal and human investigations

M Shukla, B Vincent - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Diverse intellectual functions including memory are some important aspects of cognition.
Dopamine is a neurotransmitter of the catecholamine family, which contributes to the …

Sleep deprivation leads to further impairment of hippocampal synaptic plasticity by suppressing melatonin secretion in the pineal gland of chronically unpredictable …

ZR Li, DG Liu, S Xie, YH Wang, YS Han, CY Li… - European Journal of …, 2022 - Elsevier
There has been ample research showing that insomnia is a potential trigger of depression
as well as a symptom of depression. These two factors contribute to behavioural problems …

From metabolism to behaviour–Multilevel effects of environmental methamphetamine concentrations on fish

MES Santos, P Horký, K Grabicová, C Steinbach… - Science of The Total …, 2023 - Elsevier
Methamphetamine (METH) is a concerning drug of abuse that produces strong
psychostimulant effects. The use of this substance, along with the insufficient removal in the …

Melatonin treatment improves cognitive deficits by altering inflammatory and neurotrophic factors in the hippocampus of obese mice

S Mansouri, AA Salari, A Abedi, P Mohammadi… - Physiology & …, 2022 - Elsevier
Overweight and obesity are associated with an increased risk of developing dementia and
cognitive deficits. Neuroinflammation is one of the most important mechanisms behind …

Methamphetamine and the brain: Emerging molecular targets and signaling pathways involved in neurotoxicity

SK Rashidi, F Khodagholi, S Rafie, D Kashipazha… - Toxin …, 2024 - Taylor & Francis
Methamphetamine (METH) is a psychostimulant drug widely used because of its arousing,
euphoric and hallucinogenic properties. Studies have reported that chronic METH abuse …

Heroin addiction induces axonal transport dysfunction in the brain detected by in vivo MRI

Y Luo, C Liao, L Chen, Y Zhang, S Bao, A Deng… - Neurotoxicity …, 2022 - Springer
Heroin is a highly addictive drug that causes axonal damage. Here, manganese-enhanced
magnetic resonance imaging (MEMRI) was used to dynamically monitor axonal transport at …

Gut Microbiota Taxon-Dependent Transformation of Microglial M1/M2 Phenotypes Underlying Mechanisms of Spatial Learning and Memory Impairment after Chronic …

Y Wu, Z Dong, X Jiang, L Qu, W Zhou, X Sun… - Microbiology …, 2023 - Am Soc Microbiol
Methamphetamine (METH) exposure may lead to cognitive impairment. Currently, evidence
suggests that METH exposure alters the configuration of the gut microbiota. However, the …

Homocysteine impedes neurite outgrowth recovery after intracerebral haemorrhage by downregulating pCAMK2A

G Guo, J Yang, W Guo, H Deng, H Yu, S Bai… - Stroke and Vascular …, 2023 - svn.bmj.com
Hyperhomocysteinemia (HHcy) is independently associated with poorer long-term
prognosis in patients with intracerebral haemorrhage (ICH); however, the effect and …

Melatonin blocks morphine-induced place preference: involvement of GLT-1, NF-κB, BDNF, and CREB in the nucleus accumbens

BS Alghamdi, FS Alshehri - Frontiers in Behavioral Neuroscience, 2021 - frontiersin.org
Opioid addiction remains a widespread issue despite continuous attempts by the FDA to
help maintain abstinence. Melatonin is a neurohormone considered to be involved only in …

Astrogliosis and compensatory neurogenesis after the first ethanol binge drinking‐like exposure in the adolescent rat

C Vilpoux, G Fouquet, C Deschamps… - Alcoholism: Clinical …, 2022 - Wiley Online Library
Background Multiple ethanol binge drinking‐like exposures during adolescence in the rat
induce neuroinflammation, loss of neurogenesis, and cognitive deficits in adulthood …