Nitrogen is an essential macronutrient for plant growth. Following uptake from the soil or
assimilation within the plant, organic nitrogen compounds are transported between …

Leishmania is a protozoan parasite that alternates its life cycle between the sand fly and the
mammalian host macrophages, involving several environmental changes. The parasite …

Leishmania are protozoan parasites that replicate within mature phagolysosomes of
mammalian macrophages. To define the biochemical composition of the phagosome and …

Abstract Background Pentavalent antimonials (Sb (V)) such as meglumine antimoniate
(Glucantime®) and sodium stibogluconate (Pentostam®) are used as first‐line treatments for …

Members of the family Trypanosomatidae infect many organisms, including animals, plants
and humans. Plant-infecting trypanosomes are grouped under the single genus …

We describe the first functional and molecular characterization of an amino acid permease
(LdAAP3) from the human parasitic protozoan Leishmania donovani, the causative agent of …

Background Motif discovery aims to detect short, highly conserved patterns in a collection of
unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to increase …

Parasitic protozoa, such as malaria parasites, trypanosomes, and Leishmania, acquire a
plethora of nutrients from their hosts, employing transport proteins located in the plasma …

Arginine is an essential amino acid for the human pathogen Leishmania but not to its host.
Thus, the mechanism by which this protozoan parasite regulates cellular homeostasis of …

Leishmania spp. are sandfly-transmitted protozoa parasites that cause a spectrum of
diseases in humans. Many enzymes involved in Leishmania central carbon metabolism …