Sepsis is a systemic response to infection with life-threatening consequences. Our
understanding of the molecular and cellular impact of sepsis across organs remains …

Adult tissue-resident macrophages (RMs) are either maintained by blood monocytes or
through self-renewal. While the presence of a nurturing niche is likely crucial to support the …

Loss of muscle mass is a common manifestation of chronic disease. We find the canonical
Wnt pathway to be activated in mesenchymal progenitors (MPs) from cancer-induced …

Abdominal wall defects are a frequently occurring condition in surgical practice. The most
important are material structure and biocompatibility. In this study, polylactic acid (PLA) …

Immune cell-driven pathways are linked to cancer cachexia. Tumor presence is associated
with immune cell infiltration whereas cytotoxic chemotherapies reduce immune cell counts …

Skeletal muscle regeneration depends on the function of fibro/adipogenic progenitors
(FAPs). Here we show that aging impairs myogenic stem cells and immunomodulatory …

Sepsis is a systemic response to infection with life-threatening consequences. Our
understanding of the impact of sepsis across organs of the body is rudimentary. Here, using …

Regenerative medicine aims to understand the cellular and molecular processes underlying
effective tissue repair with the long-term goal of restoring structure and function to damaged …

Skeletal muscle regeneration depends on the function of fibro/adipogenic progenitors
(FAPs). Here we show that aging impairs myogenic stem cells and immunomodulatory …

Muscle regeneration is a highly orchestrated process in which multiple tissue-resident and
infiltrating cells actively participate to ensure optimal repair and functional recovery. More …