Water pollution has become a serious issue, and mercury (II) ion (Hg (II)) is highly toxic even at low concentrations. Therefore, Hg (II) concentration should be strictly monitored. This …
IF de Farias, R de Oliveira Gonçalves… - Journal of Molecular …, 2023 - Elsevier
Pyrazolines are heterocyclic compounds with nitrogen-containing rings, known mainly for their pharmacological potential. In recent times, much attention has been paid to the …
Protein kinase dysregulation induces cancer cell aggressiveness leading to rapid tumor progression and poor prognosis in TNBC patients. Many small-molecule kinase inhibitors …
Thioxanthone derivatives were docked, synthesized, and tested for their anticancer activity. The molecular docking results showed that 1‐hydroxythioxanthone, 2‐chloro‐1 …
To enhance the effectiveness of chemotherapy and overcome resistance, scientists must develop novel drugs or scaffolds that have a combined effect, such as the inhibition of EGFR …
Schiff bases are significant compounds that occur naturally or can be synthesized in laboratory settings. In this study, we synthesized three novel Schiff bases, designated as …
Background Multidrug resistance in various cancer types is a major obstacle in cancer treatment. The concept of a single drug molecular target often causes treatment failure due …
One of the most typical cancers to affect women worldwide is breast cancer. Multiple routes involving different proteins that control the development of cancer. HER-2 is a protein that …
S Mudimela, S Janardhanan - Asian Journal of Organic …, 2023 - Wiley Online Library
Neuro‐inflammatory responses lead to various neurodegenerative disorders. A small library of 1H‐pyrazole‐1‐carbothioamidoacetamido)‐furan‐3‐carboxamide molecular hybrids …