Current cancer epidemiology

C Mattiuzzi, G Lippi - Journal of epidemiology and global health, 2019 - Springer
In this brief report, we offer a concise overview on current cancer epidemiology garnered
from the official databases of World Health Organization and American Cancer Society and …

[HTML][HTML] The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring

SM Batool, A Yekula, P Khanna, T Hsia… - Cell Reports …, 2023 - cell.com
The emerging field of liquid biopsy stands at the forefront of novel diagnostic strategies for
cancer and other diseases. Liquid biopsy allows minimally invasive molecular …

Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study

DG Rothwell, M Ayub, N Cook, F Thistlethwaite… - Nature medicine, 2019 - nature.com
Next-generation sequencing (NGS) of circulating tumor DNA (ctDNA) supports blood-based
genomic profiling but is not yet routinely implemented in the setting of a phase I trials clinic …

ctDNA as a cancer biomarker: A broad overview

LS Pessoa, M Heringer, VP Ferrer - Critical reviews in oncology …, 2020 - Elsevier
Circulating tumor DNA (ctDNA) in fluids has gained attention because ctDNA seems to
identify tumor-specific abnormalities, which could be used for diagnosis, follow-up of …

Updates on liquid biopsy: Current trends and future perspectives for clinical application in solid tumors

P Pinzani, V D'Argenio, M Del Re… - Clinical Chemistry and …, 2021 - degruyter.com
Despite advances in screening and therapeutics cancer continues to be one of the major
causes of morbidity and mortality worldwide. The molecular profile of tumor is routinely …

Isolation of circulating tumor cells in non-small-cell-lung-cancer patients using a multi-flow microfluidic channel

J Zhou, A Kulasinghe, A Bogseth, K O'Byrne… - Microsystems & …, 2019 - nature.com
Circulating tumor cells (CTCs) carry a wealth of information on primary and metastatic
tumors critical for precise cancer detection, monitoring, and treatment. Numerous …

Potential utility of liquid biopsy as a diagnostic and prognostic tool for the assessment of solid tumors: implications in the precision oncology

RA Mathai, RVS Vidya, BS Reddy, L Thomas… - Journal of clinical …, 2019 - mdpi.com
Liquid biopsy is a technique that utilizes circulating biomarkers in the body fluids of cancer
patients to provide information regarding the genetic landscape of the cancer. It is emerging …

Personalized ctDNA for monitoring disease status in head and neck squamous cell carcinoma

GJ Hanna, MJ Dennis, N Scarfo, MS Mullin… - Clinical Cancer …, 2024 - aacrjournals.org
Purpose: Many patients with locoregionally advanced human papillomavirus–negative head
and neck squamous cell carcinoma (HNSCC) relapse. ctDNA has the potential to identify …

[HTML][HTML] Genetic and epigenetic alterations of colorectal cancer

SN Hong - Intestinal research, 2018 - synapse.koreamed.org
Colorectal cancer (CRC) arise from multi-step carcinogenesis due to genetic mutations and
epigenetic modifications of human genome. Genetic mutations and epigenetic modifications …

Human germ cell tumors are developmental cancers: impact of epigenetics on pathobiology and clinic

J Lobo, AJM Gillis, C Jerónimo, R Henrique… - International journal of …, 2019 - mdpi.com
Current (high throughput omics-based) data support the model that human (malignant) germ
cell tumors are not initiated by somatic mutations, but, instead through a defined locked …