Benzofuran moiety is the main component of many biologically active natural and synthetic
heterocycles. These heterocycles have unique therapeutic potentials and are involved in …

Abstract According to the World Health Organization (WHO) statistics: In 2020, there were
2.3 million women diagnosed with breast cancer and 685,000 deaths globally. Therefore …

Cancer, which has been cursed for human beings for long time is considered as one of the
leading causes of morbidity and mortality across the world. In spite of different types of …

Pim-1 kinase targeted recently has proved an essential goal of breast cancer therapy. We
report the design, synthesis with full characterization analysis of pyrazolo [3, 4-b] pyridine …

One crucial strategy for the treatment of breast cancer involves focusing on the Vascular
Endothelial Growth Factor Receptor (VEGFR-2) signaling system. Consequently, the …

Terephthalohydrazide chitosan hydrogel (TCs) was prepared and investigated as an
ecofriendly biopolymeric catalyst for synthesis of some novel thiazole and thiadiazole …

Liver cancer is the most common type of cancer in many countries. New studies and
statistics show rising liver cancer worldwide, so it is essential to seek new agents for this …

A multicomponent synthesis was empolyed for the synthesis of ethyl 2-amino-4, 5, 6, 7-
tetrahydrobenzo [b] thiophene-3-carboxylate 1. An interesting cyclization was obtained …

In continuation of our interest on the synthesis of fused quinoxalines and pyrazines
derivatives and due to the resultant pharmacological interest in compounds which belong to …

Worldwide, cancer is still an area with high unmet medical need. Lead optimization efforts
towards structure-based drug design were employed to discover newly synthesized hetero …