Proposed refined diagnostic criteria and classification of eosinophil disorders and related syndromes
P Valent, AD Klion, F Roufosse, D Simon… - Allergy, 2023 - Wiley Online Library
Eosinophilia and eosinophil activation are recurrent features in various reactive states and
certain hematologic malignancies. In patients with hypereosinophilia (HE), HE‐induced …
certain hematologic malignancies. In patients with hypereosinophilia (HE), HE‐induced …
OF THE WORLD HEALTH ORGANIZATION CLASSIFICATION OF TUMORS OF THE HEMATOPOIETIC AND LYMPHOID TISSUES
This manuscript represents a review of lymphoblastic leukemia/lymphoma (acute
lymphoblastic leukemia/lymphoblastic lymphoma), acute leukemias of ambiguous lineage …
lymphoblastic leukemia/lymphoblastic lymphoma), acute leukemias of ambiguous lineage …
Targeting the PDGF signaling pathway in tumor treatment
CH Heldin - Cell Communication and Signaling, 2013 - Springer
Platelet-derived growth factor (PDGF) isoforms and PDGF receptors have important
functions in the regulation of growth and survival of certain cell types during embryonal …
functions in the regulation of growth and survival of certain cell types during embryonal …
Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes
P Valent, AD Klion, HP Horny, F Roufosse… - Journal of Allergy and …, 2012 - Elsevier
Eosinophilia is an important indicator of various neoplastic and nonneoplastic conditions.
Depending on the underlying disease and mechanisms, eosinophil infiltration can lead to …
Depending on the underlying disease and mechanisms, eosinophil infiltration can lead to …
[HTML][HTML] Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia
Genomic profiling has identified a subtype of high-risk B-progenitor acute lymphoblastic
leukemia (B-ALL) with alteration of IKZF1, a gene expression profile similar to BCR-ABL1 …
leukemia (B-ALL) with alteration of IKZF1, a gene expression profile similar to BCR-ABL1 …
Myeloid neoplasms with eosinophilia
A Reiter, J Gotlib - Blood, The Journal of the American Society …, 2017 - ashpublications.org
Molecular diagnostics has generated substantial dividends in dissecting the genetic basis of
myeloid neoplasms with eosinophilia. The family of diseases generated by dysregulated …
myeloid neoplasms with eosinophilia. The family of diseases generated by dysregulated …
The secret ally: immunostimulation by anticancer drugs
It has recently become clear that the tumour microenvironment, and in particular the immune
system, has a crucial role in modulating tumour progression and response to therapy …
system, has a crucial role in modulating tumour progression and response to therapy …
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
SG O'Brien, F Guilhot, RA Larson… - … England Journal of …, 2003 - Mass Medical Soc
Background Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high
response rates in patients with chronic-phase chronic myeloid leukemia (CML) who have …
response rates in patients with chronic-phase chronic myeloid leukemia (CML) who have …
Role of platelet-derived growth factors in physiology and medicine
J Andrae, R Gallini, C Betsholtz - Genes & development, 2008 - genesdev.cshlp.org
Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) have served as
prototypes for growth factor and receptor tyrosine kinase function for more than 25 years …
prototypes for growth factor and receptor tyrosine kinase function for more than 25 years …
[HTML][HTML] Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
Polycythemia vera (PV), essential thrombocythemia (ET), and myeloid metaplasia with
myelofibrosis (MMM) are clonal disorders arising from hematopoietic progenitors. An …
myelofibrosis (MMM) are clonal disorders arising from hematopoietic progenitors. An …