The vitamin D receptor (VDR) belongs to the nuclear receptor superfamily of transcription
factors. The VDR is expressed in diverse brain regions and has been implicated in the …

Alzheimer's disease (AD) is the most prevalent form of dementia. The exact pathophysiology
of this disease remains incompletely understood and safe and effective therapies are …

Since its discovery during the epidemic of rickets in the early 1920s, the physiological effects
of vitamin D on calcium/phosphorus homeostasis have been thoroughly studied. Along with …

Neurodegenerative diseases (NDs) represent a common neurological pathology that
determines a progressive deterioration of the brain or the nervous system. For treating NDs …

The impairment of hippocampal neurogenesis at the early stages of Alzheimer's disease
(AD) is believed to support early cognitive decline. Converging studies sustain the idea that …

Mushrooms have long been used not only as food but also for the treatment of various
ailments. Although at its infancy, accumulated evidence suggested that culinary-medicinal …

It has been 20 years since we first proposed vitamin D as a “possible” neurosteroid.(1) Our
work over the last two decades, particularly results from our cellular and animal models, has …

There are about 3000 species of mushrooms, which have a high amount of substances that
are beneficial to human health, such as antioxidants. It is well known that oxidative stress …

Vitamin D deficiency is believed to affect between 35 and 55% of the world's population,
making it a hidden pandemic. In addition to its role in bone and calcium homeostasis …

Background The deficiency of vitamin D has been widely reported all over the world and
linked to several chronic diseases. Mushrooms are valuable nutritional foods with …