Use of Lawesson's reagent in organic syntheses
Transformation of a carbonyl functional group into thiocarbonyl has been an important
interest to synthetic organic chemists for many years. Two reagents, phosphorus …
interest to synthetic organic chemists for many years. Two reagents, phosphorus …
Bioactivity profile of the diterpene isosteviol and its derivatives
Steviosides, rebaudiosides and their analogues constitute a major class of naturally
occurring biologically active diterpene compounds. The wide spectrum of pharmacological …
occurring biologically active diterpene compounds. The wide spectrum of pharmacological …
Novel N-bridged pyrazole-1-carbothioamides With Potential Antiproliferative Activity: design, synthesis, In Vitro and In Silico Studies
Thiazole-substituted pyrazole is an important structural feature of many bioactive
compounds, including antiviral, antitubercular, analgesic and anticancer agents. Herein we …
compounds, including antiviral, antitubercular, analgesic and anticancer agents. Herein we …
Controlled release of 5-fluorouracil to melanoma cells using a hydrogel/micelle composites based on deoxycholic acid and carboxymethyl chitosan
Z Pourmanouchehri, S Ebrahimi, M Limoee… - International journal of …, 2022 - Elsevier
Fluorouracil (5-FU) is an antimetabolite drug widely used for the treatment of skin cancer.
Despite its proven efficacy in treating malignancies, its systemic administration is limited due …
Despite its proven efficacy in treating malignancies, its systemic administration is limited due …
Design and stereoselective synthesis of novel isosteviol-fused pyrazolines and pyrazoles as potential anticancer agents
SL Zhu, Y Wu, CJ Liu, CY Wei, JC Tao… - European Journal of …, 2013 - Elsevier
Two series of novel isosteviol-fused pyrazoline and pyrazole derivatives were facilely
synthesized via intramolecular 1, 3-dipolar cycloaddition and condensation reaction …
synthesized via intramolecular 1, 3-dipolar cycloaddition and condensation reaction …
Updates in bile acid-bioactive molecule conjugates and their applications
Bile acid conjugates are emerging as important chemical resources due to their low cost and
wide availability of bile acids, making them privileged molecules in drug carrier systems and …
wide availability of bile acids, making them privileged molecules in drug carrier systems and …
Synthesis of novel steroidal heterocyclic derivatives as antibacterial agents
MM Abdelhalim, MMT El-Saidi, ST Rabie… - Steroids, 2007 - Elsevier
This study aimed at the synthesis of novel structurally promising steroidal heterocycles and
to elucidate the potential role of these compounds as antibacterial agents. Epi-androsterone …
to elucidate the potential role of these compounds as antibacterial agents. Epi-androsterone …
Heterocyclizations of pregnenolone: Novel synthesis of thiosemicarbazone, thiophene, thiazole, thieno [2, 3-b] pyridine derivatives and their cytotoxicity evaluations
RM Mohareb, WW Wardakhan, GA Elmegeed… - Steroids, 2012 - Elsevier
Pregnenolone (1) was used as a template to develop new anticancer compounds. Ring D
modification of 1 through its reaction with 4-phenyl-3-thiosemicarbazide gave the …
modification of 1 through its reaction with 4-phenyl-3-thiosemicarbazide gave the …
Bile acid-based receptors and their applications in recognition
Ion recognition has attracted great attention in the past decades because of its important role
in biology, medicine, environment, and chemistry. The combination of rigidity, curved …
in biology, medicine, environment, and chemistry. The combination of rigidity, curved …
Recent advances in thionating reagents for the synthesis of organosulfur compounds
V Polshettiwar, MP Kaushik - Journal of Sulfur Chemistry, 2006 - Taylor & Francis
Thionation is the most suitable and efficient method for the synthesis of organosulfur
compounds. Thio-compounds are important intermediates in the synthesis of various …
compounds. Thio-compounds are important intermediates in the synthesis of various …