Background Prenatal and perinatal insults are implicated in the aetiopathogenesis of
psychotic disorders but the consistency and magnitude of their associations with psychosis …

Schizophrenia is a devastating mental illness with a strong genetic component that is the
subject of extensive research. Despite the high heritability, it is well recognized that non …

Schizophrenia is a severe neuropsychiatric disorder with persistence of symptoms
throughout adult life in most of the affected patients. This unfavorable course is associated …

Schizophrenia is a heterogeneous psychiatric disorder, which can severely impact social
and professional functioning. Epidemiological and clinical studies show that schizophrenia …

Schizophrenia was initially defined as “dementia praecox” by E. Kraepelin, which implies
progressive deterioration. However, recent studies have revealed that early effective …

People with psychotic disorders can show marked interindividual variations in the onset of
illness, responses to treatment and relapse, but they receive broadly similar clinical care …

Early identification and treatment significantly improve clinical outcomes of psychotic
disorders. Recent studies identified protein components of the complement and coagulation …

Schizophrenia is a major psychotic disorder with multifactorial etiology that includes
interactions between genetic vulnerability and environmental risk factors. In addition …

Brief psychotic episodes represent an intriguing paradox in clinical psychiatry because they
elude the standard knowledge that applies to the persisting psychotic disorders such as …

Stress has repeatedly been implicated in the onset and exacerbation of positive symptoms
of psychosis. Increasing interest is growing for the role of psychosocial stress in the …