Pharmacometabolomics in drug disposition, toxicity and precision medicine
GR Trevor, YJ Lim, BL Urquhart - Drug Metabolism and Disposition, 2024 - ASPET
The precision medicine initiative has driven a substantial change in the way scientists and
health care practitioners think about diagnosing and treating disease. While it has long been …
health care practitioners think about diagnosing and treating disease. While it has long been …
Metabolomic identification of predictive and early biomarkers of cisplatin‐induced acute kidney injury in adult head and neck cancer patients
YJ Lim, SG Xiu, MS Kuruvilla, E Winquist… - British Journal of …, 2024 - Wiley Online Library
Aim Cisplatin causes acute kidney injury (AKI) in approximately one third of patients. Serum
creatinine and urinary output are poor markers of cisplatin‐induced AKI. Metabolomics was …
creatinine and urinary output are poor markers of cisplatin‐induced AKI. Metabolomics was …