Hepatitis B virus (HBV) contributes to hepatocellular carcinoma (HCC) development through
direct and indirect mechanisms. HBV DNA integration into the host genome occurs at early …

Polycomb group proteins have long been linked to the occurrence of different forms of
cancer. Polycomb proteins form at least two distinct complexes, the Polycomb-repressive …

In recent years, long noncoding RNAs (lncRNAs) have been shown to have critical
regulatory roles in cancer biology. However, the contributions of lncRNAs to hepatitis B virus …

Epigenetic alterations and microRNA (miRNA) deregulation are common in hepatocellular
carcinoma (HCC). The histone H3 lysine 27 (H3K27) tri‐methylating enzyme, enhancer of …

The discovery that cancer can be governed above and beyond the level of our DNA
presents a new era for designing therapies that reverse the epigenetic state of a tumour cell …

Hepatitis C virus (HCV) is a major leading cause of hepatocellular carcinoma (HCC). HCV-
induced hepatocarcinogenesis is a multistep process resulting from a combination of …

Background Epithelial-mesenchymal transition (EMT) is the key process driving cancer
metastasis. Oncogene/self renewal factor BMI-1 has been shown to induce EMT in cancer …

Knowledge of the fundamental epigenetic mechanisms governing gene expression and
cellular phenotype are sufficiently advanced that novel insights into the epigenetic control of …

Natural killer (NK) cell-mediated tumor cell eradication could inhibit tumor initiation and
progression. However, the factors that regulate NK cell-mediated cancer cell eradication …

Background & Aims Oncogene polycomb group protein enhancer of zeste homolog 2
(EZH2) has been proposed to be a target gene of putative tumor suppressor microRNA-101 …