[图书][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Long noncoding RNA (lncRNA): a target in neuropathic pain

S Wu, J Bono, YX Tao - Expert opinion on therapeutic targets, 2019 - Taylor & Francis
Introduction: Current treatments for neuropathic pain are limited in part due to the incomplete
understanding of its underlying mechanisms. Recent evidence reveals the dysregulated …

How miRNAs regulate schwann cells during peripheral nerve regeneration—A systemic review

A Borger, S Stadlmayr, M Haertinger… - International journal of …, 2022 - mdpi.com
A growing body of studies indicate that small noncoding RNAs, especially microRNAs
(miRNA), play a crucial role in response to peripheral nerve injuries. During Wallerian …

Shedding light on emerging therapeutic targets for chordoma

M Martinez Moreno, E Wang, C Schroeder… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Despite encouraging advances in radiation and surgical treatment, chordomas
remain resistant to chemotherapy and local recurrence is common. Although the primary …

The etiological roles of miRNAs, lncRNAs, and circRNAs in neuropathic pain: a narrative review

M Jiang, Y Wang, J Wang, S Feng… - Journal of clinical …, 2022 - Wiley Online Library
Abstract Background Non‐coding RNAs (ncRNAs) are involved in neuropathic pain
development. Herein, we systematically searched for neuropathic pain‐related ncRNAs …

Non-coding RNAs in neuropathic pain

T Kalpachidou, KK Kummer, M Kress - Neuronal signaling, 2020 - portlandpress.com
Neuro-immune alterations in the peripheral and central nervous system play a role in the
pathophysiology of chronic pain in general, and members of the non-coding RNA (ncRNA) …

RNA-seq reveals sex differences in gene expression during peripheral neuropathic inflammation and in pain relief from a COX-2 inhibiting theranostic nanoemulsion

B Deal, K Phillips, C Crelli, JM Janjic… - International Journal of …, 2023 - mdpi.com
Given decades of neuroinflammatory pain research focused only on males, there is an
urgent need to better understand neuroinflammatory pain in females. This, paired with the …

PIAS1 alleviates diabetic peripheral neuropathy through SUMOlation of PPAR-γ and miR-124-induced downregulation of EZH2/STAT3

Z Hou, J Chen, H Yang, X Hu, F Yang - Cell Death Discovery, 2021 - nature.com
Diabetic peripheral neuropathy (DPN) is a frequently occurring chronic complication of
diabetes. In this study, we aim to explore the regulatory mechanism of protein inhibitor of …

Role of long noncoding RNAs and circular RNAs in nerve regeneration

C Yao, B Yu - Frontiers in Molecular Neuroscience, 2019 - frontiersin.org
Nerve injuries may cause severe disability and affect the quality of life. It is of great
importance to get a full understanding of the biological processes and molecular …

Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination

P Ayuso-García, A Sánchez-Rueda… - Science …, 2024 - science.org
Myelination is essential for neuronal function and health. In peripheral nerves,> 100
causative mutations have been identified that cause Charcot-Marie-Tooth disease, a …