In this review we summarize recent major advances in our understanding on the molecular
mechanisms, mediators, and biomarkers of acute lung injury (ALI) and alveolar-capillary …

The receptor for advanced glycation end products (RAGE) is a transmembrane receptor that
belongs to the immunoglobulin superfamily and is extensively associated with chronic …

Rationale: Sevoflurane improves gas exchange, and reduces alveolar edema and
inflammation in preclinical studies of lung injury, but its therapeutic effects have never been …

Purpose The soluble receptor for advanced glycation end-products (sRAGE) is a marker of
lung epithelial injury and alveolar fluid clearance (AFC), with promising values for assessing …

Abstract Coronavirus Disease 2019 (COVID-19), caused by the novel virus SARS-CoV-2, is
often more severe in older adults. Besides age, other underlying conditions such as obesity …

The unique characteristics of pulmonary circulation and alveolar-epithelial capillary-
endothelial barrier allow for maintenance of the air-filled, fluid-free status of the alveoli …

Cellular and molecular mechanisms driving morbidity following SARS-CoV-2 infection have
not been well defined. The receptor for advanced glycation end products (RAGE) is a central …

Acute respiratory distress syndrome (ARDS) is a common condition associated with critically
ill patients, characterized by bilateral chest radiographical opacities with refractory …

Background During ARDS, CT can reveal two distinct lung imaging patterns, focal or
nonfocal, with different responses to positive end-expiratory pressure, recruitment …

Pulmonary fibrosis (PF) is characterized by inflammation and fibrosis of the interstitium and
destruction of alveolar histoarchitecture ultimately leading to a fatal impairment of lung …