Advances in fatty acids nutrition in dairy cows: from gut to cells and effects on performance

M Bionaz, E Vargas-Bello-Pérez, S Busato - Journal of Animal Science …, 2020 - Springer
High producing dairy cows generally receive in the diet up to 5–6% of fat. This is a relatively
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …

Biosynthesis of milk fat, protein, and lactose: roles of transcriptional and posttranscriptional regulation

JS Osorio, J Lohakare, M Bionaz - Physiological genomics, 2016 - journals.physiology.org
The demand for high-quality milk is increasing worldwide. The efficiency of milk synthesis
can be improved by taking advantage of the accumulated knowledge of the transcriptional …

Cytotoxicity of apigenin toward multiple myeloma cell lines and suppression of iNOS and COX-2 expression in STAT1-transfected HEK293 cells

AN Adham, S Abdelfatah, AM Naqishbandi… - Phytomedicine, 2021 - Elsevier
Background Apigenin is one of the most abundant dietary flavonoids that possesses multiple
bio-functions. Purpose This study was designed to determine the influence of apigenin on …

CRISPR/Cas9-mediated stearoyl-CoA desaturase 1 (SCD1) deficiency affects fatty acid metabolism in goat mammary epithelial cells

H Tian, J Luo, Z Zhang, J Wu, T Zhang… - Journal of agricultural …, 2018 - ACS Publications
Stearoyl-CoA desaturase 1 (SCD1) is a fatty acid desaturase catalyzing cis-double-bond
formation in the Δ9 position to produce monounsaturated fatty acids essential for the …

Characterization of sheep milk extracellular vesicle-miRNA by sequencing and comparison with cow milk

S Quan, X Nan, K Wang, L Jiang, J Yao, B Xiong - Animals, 2020 - mdpi.com
Simple Summary Milk provides significant health benefits for mammals, especially as the
primary nutrient sources of neonates. Milk was recognized as the epigenetic “doping …

[HTML][HTML] Fish oil-induced milk fat depression and associated downregulation of mammary lipogenic genes in dairy ewes

D Carreño, G Hervás, PG Toral, T Castro-Carrera… - Journal of Dairy …, 2016 - Elsevier
Several studies in dairy cows have shown a relationship between milk fat depression (MFD)
and alterations caused in lipogenic gene expression by dietary nutrients. However …

[HTML][HTML] A canonical discriminant analysis to study the association between milk fatty acids of ruminal origin and milk fat depression in dairy cows

G Conte, C Dimauro, A Serra, NPP Macciotta… - Journal of Dairy …, 2018 - Elsevier
Although milk fat depression (MFD) has been observed and described since the beginning
of the last century, all the molecular and biochemical mechanisms involved are still not …

High rumen degradable starch decreased goat milk fat via trans-10, cis-12 conjugated linoleic acid-mediated downregulation of lipogenesis genes, particularly …

L Zheng, S Wu, J Shen, X Han, C Jin, X Chen… - Journal of Animal …, 2020 - Springer
Background Starch is an important substance that supplies energy to ruminants. To provide
sufficient energy for high-yielding dairy ruminants, they are typically fed starch-enriched …

[HTML][HTML] Activation of liver X receptor promotes fatty acid synthesis in goat mammary epithelial cells via modulation of SREBP1 expression

HF Xu, J Luo, XY Zhang, J Li, M Bionaz - Journal of dairy science, 2019 - Elsevier
In bovine mammary tissue and cells, liver X receptor (LXR) regulates lipid synthesis mainly
via transactivation of the transcription factor sterol regulatory element binding protein 1 …

Genome-wise enGineerinG of ruminant nutrition–nutriGenomics: applications, challenGes, and future perspectives–a review

M Kizilaslan, Y Arzik, MU Cinar, Y Konca - Annals of Animal Science, 2022 - sciendo.com
1Department of Animal Breeding and Genetics, International Center for Livestock Research
and Training, 06852, Ankara, Turkey 2Faculty of Agriculture, Erciyes University, 38030 …