Colistin, also known as polymyxin E, is an antimicrobial agent that is effective against a variety of Gram-negative bacilli, especially the Enterobacteriaceae family. Recently, the wide …
M Mmatli, NM Mbelle, J Osei Sekyere - Frontiers in Cellular and …, 2022 - frontiersin.org
Background Mobile colistin resistance (mcr) genes modify Lipid A molecules of the lipopolysaccharide, changing the overall charge of the outer membrane. Results and …
Y Shen, R Zhang, S Schwarz, C Wu… - Environmental …, 2020 - Wiley Online Library
Colistin resistance has attracted substantial attention after colistin was considered as a last‐ resort drug for the treatment of infections caused by carbapenem‐resistant and/or multidrug …
Mobile colistin resistance (mcr) genes (mcr-1 to mcr-10) are plasmid-encoded genes that threaten the clinical utility of colistin (COL), one of the highest-priority critically important …
The use of contaminated water has been associated with severe disease outbreaks. Due to widespread pollution with untreated sewage, concerns have been raised over water quality …
Plasmid-borne colistin resistance is considered one of the most complex public health concerns worldwide. Several studies reported the presence of the mcr-1.1 harboring …
Colistin, a last resort antibiotic, is important for controlling infections with carbapenem- resistant Enterobacteriaceae. The recent emergence of mobile-colistin-resistance (mcr) …
C Bastidas-Caldes, S Guerrero-Freire… - … de Salud Pública, 2023 - SciELO Public Health
Objective. Colistin is an antibiotic of last resort for treating serious Gram-negative bacterial infections. However, the misuse of colistin, especially as an animal growth promoter, has …
Antibiotics can truly be considered the symbol of the 20th century's miracle drugs. However, excessive and inappropriate use of antibiotics in human and veterinary medicine has led to …