Worldwide Prevalence of mcr-mediated Colistin-Resistance Escherichia coli in Isolates of Clinical Samples, Healthy Humans, and Livestock—A Systematic Review …

C Bastidas-Caldes, JH de Waard, MS Salgado… - Pathogens, 2022 - mdpi.com
Background: Antimicrobial resistance is a serious public-health problem throughout the
world. Escherichia coli, the most common Gram-negative microorganism, has developed …

[HTML][HTML] An overview of colistin resistance, mobilized colistin resistance genes dissemination, global responses, and the alternatives to colistin: a review

MH Gharaibeh, SQ Shatnawi - Veterinary world, 2019 - ncbi.nlm.nih.gov
Colistin, also known as polymyxin E, is an antimicrobial agent that is effective against a
variety of Gram-negative bacilli, especially the Enterobacteriaceae family. Recently, the wide …

Global epidemiology, genetic environment, risk factors and therapeutic prospects of mcr genes: A current and emerging update

M Mmatli, NM Mbelle, J Osei Sekyere - Frontiers in Cellular and …, 2022 - frontiersin.org
Background Mobile colistin resistance (mcr) genes modify Lipid A molecules of the
lipopolysaccharide, changing the overall charge of the outer membrane. Results and …

Farm animals and aquaculture: significant reservoirs of mobile colistin resistance genes

Y Shen, R Zhang, S Schwarz, C Wu… - Environmental …, 2020 - Wiley Online Library
Colistin resistance has attracted substantial attention after colistin was considered as a last‐
resort drug for the treatment of infections caused by carbapenem‐resistant and/or multidrug …

Mobile Colistin Resistance (mcr) Gene-Containing Organisms in Poultry Sector in Low- and Middle-Income Countries: Epidemiology, Characteristics, and One Health …

MU Anyanwu, IF Jaja, COR Okpala, EO Njoga… - Antibiotics, 2023 - mdpi.com
Mobile colistin resistance (mcr) genes (mcr-1 to mcr-10) are plasmid-encoded genes that
threaten the clinical utility of colistin (COL), one of the highest-priority critically important …

Nationwide Assessment of Water Quality in Rivers across Lebanon by Quantifying Fecal Indicators Densities and Profiling Antibiotic Resistance of Escherichia coli

LA Dagher, J Hassan, S Kharroubi, H Jaafar, II Kassem - Antibiotics, 2021 - mdpi.com
The use of contaminated water has been associated with severe disease outbreaks. Due to
widespread pollution with untreated sewage, concerns have been raised over water quality …

First report from supermarket chicken meat and genomic characterization of colistin resistance mediated by mcr-1.1 in ESBL-producing, multidrug-resistant Salmonella …

I Habib, M Elbediwi, A Ghazawi, MYI Mohamed… - International Journal of …, 2022 - Elsevier
Plasmid-borne colistin resistance is considered one of the most complex public health
concerns worldwide. Several studies reported the presence of the mcr-1.1 harboring …

The Mobile Colistin Resistance Gene, mcr-1.1, Is Carried on IncX4 Plasmids in Multidrug Resistant E. coli Isolated from Rainbow Trout Aquaculture

J Hassan, RZ Eddine, D Mann, S Li, X Deng, IP Saoud… - Microorganisms, 2020 - mdpi.com
Colistin, a last resort antibiotic, is important for controlling infections with carbapenem-
resistant Enterobacteriaceae. The recent emergence of mobile-colistin-resistance (mcr) …

Colistin resistance in Escherichia coli and Klebsiella pneumoniae in humans and backyard animals in Ecuador

C Bastidas-Caldes, S Guerrero-Freire… - … de Salud Pública, 2023 - SciELO Public Health
Objective. Colistin is an antibiotic of last resort for treating serious Gram-negative bacterial
infections. However, the misuse of colistin, especially as an animal growth promoter, has …

Epidemiology of antimicrobial resistance in Lebanese extra-hospital settings: An overview

M Osman, H Al Mir, R Rafei, F Dabboussi… - Journal of global …, 2019 - Elsevier
Antibiotics can truly be considered the symbol of the 20th century's miracle drugs. However,
excessive and inappropriate use of antibiotics in human and veterinary medicine has led to …