Recent advances in simultaneous thermostability-activity improvement of industrial enzymes through structure modification
Engineered thermostable microbial enzymes are widely employed to catalyze chemical
reactions in numerous industrial sectors. Although high thermostability is a prerequisite of …
reactions in numerous industrial sectors. Although high thermostability is a prerequisite of …
Nature‐Inspired Electrocatalysts for CO2 Reduction to C2+ Products
L Xu, P Trogadas, MO Coppens - Advanced Energy Materials, 2023 - Wiley Online Library
The electrocatalytic reduction reaction of carbon dioxide (CO2RR) has gained significant
attention as a promising approach to mitigate carbon dioxide emissions and generate …
attention as a promising approach to mitigate carbon dioxide emissions and generate …
Enhancing Zinc Uptake through Dual‐Modification of Cicer arietinum Protein
Zinc is crucial for physiological processes; however, deficiency persists globally. Binding
zinc to plant proteins enhances absorption, minimizing toxicity risks and offering a potential …
zinc to plant proteins enhances absorption, minimizing toxicity risks and offering a potential …
Review on NAD (P) H dehydrogenase quinone 1 (NQO1) pathway
NQO1 is an enzyme present in humans which is encoded by NQO1 gene. It is a protective
antioxidant agent, versatile cytoprotective agent and regulates the oxidative stresses of …
antioxidant agent, versatile cytoprotective agent and regulates the oxidative stresses of …
How does solvation layer mobility affect protein structural dynamics?
JN Dahanayake, KR Mitchell-Koch - Frontiers in Molecular …, 2018 - frontiersin.org
Solvation is critical for protein structural dynamics. Spectroscopic studies have indicated
relationships between protein and solvent dynamics, and rates of gas binding to heme …
relationships between protein and solvent dynamics, and rates of gas binding to heme …
Multiomic big data analysis challenges: increasing confidence in the interpretation of artificial intelligence assessments
The need for holistic molecular measurements to better understand disease initiation,
development, diagnosis, and therapy has led to an increasing number of multiomic …
development, diagnosis, and therapy has led to an increasing number of multiomic …
Stimuli-responsive pure protein organogel sensors and biocatalytic materials
NL Smith, AE Coukouma, DC Wilson… - … applied materials & …, 2019 - ACS Publications
Utilizing protein chemistry in organic solvents has important biotechnology applications.
Typically, organic solvents negatively impact protein structure and function. Immobilizing …
Typically, organic solvents negatively impact protein structure and function. Immobilizing …
Molecular mechanism of methanol inhibition in CALB-catalyzed alcoholysis: Analyzing molecular dynamics simulations by a Markov state model
Lipases are widely used enzymes that catalyze hydrolysis and alcoholysis of fatty acid
esters. At high concentrations of small alcohols such as methanol or ethanol, many lipases …
esters. At high concentrations of small alcohols such as methanol or ethanol, many lipases …
Label-free multimetric measurement of molecular binding kinetics by electrical modulation of a flexible nanobiolayer
Most label-free techniques rely on measuring refractive index or mass change on the sensor
surface. Thus, it is challenging for them to measure small molecules or enzymatic processes …
surface. Thus, it is challenging for them to measure small molecules or enzymatic processes …
[HTML][HTML] Targeting mTOR Kinase with Natural Compounds: Potent ATP-Competitive Inhibition Through Enhanced Binding Mechanisms
Background/Objectives: The mammalian target of the rapamycin (mTOR) signaling pathway
is a central regulator of cell growth, proliferation, metabolism, and survival. Dysregulation of …
is a central regulator of cell growth, proliferation, metabolism, and survival. Dysregulation of …