Bacterial motility: machinery and mechanisms

N Wadhwa, HC Berg - Nature reviews microbiology, 2022 - nature.com
Bacteria have developed a large array of motility mechanisms to exploit available resources
and environments. These mechanisms can be broadly classified into swimming in aqueous …

The promise and the challenges of cryo‐electron tomography

M Turk, W Baumeister - FEBS letters, 2020 - Wiley Online Library
Structural biologists have traditionally approached cellular complexity in a reductionist
manner in which the cellular molecular components are fractionated and purified before …

Structural basis of assembly and torque transmission of the bacterial flagellar motor

J Tan, X Zhang, X Wang, C Xu, S Chang, H Wu… - Cell, 2021 - cell.com
The bacterial flagellar motor is a supramolecular protein machine that drives rotation of the
flagellum for motility, which is essential for bacterial survival in different environments and a …

Structure and function of stator units of the bacterial flagellar motor

M Santiveri, A Roa-Eguiara, C Kühne, N Wadhwa… - Cell, 2020 - cell.com
Many bacteria use the flagellum for locomotion and chemotaxis. Its bidirectional rotation is
driven by a membrane-embedded motor, which uses energy from the transmembrane ion …

Structures of the stator complex that drives rotation of the bacterial flagellum

JC Deme, S Johnson, O Vickery, A Aron… - Nature …, 2020 - nature.com
The bacterial flagellum is the prototypical protein nanomachine and comprises a rotating
helical propeller attached to a membrane-embedded motor complex. The motor consists of a …

Ion selectivity and rotor coupling of the Vibrio flagellar sodium-driven stator unit

H Hu, PF Popp, M Santiveri, A Roa-Eguiara… - Nature …, 2023 - nature.com
Bacteria swim using a flagellar motor that is powered by stator units. Vibrio spp. are highly
motile bacteria responsible for various human diseases, the polar flagella of which are …

Structure and activity of particulate methane monooxygenase arrays in methanotrophs

Y Zhu, CW Koo, CK Cassidy, MC Spink, T Ni… - Nature …, 2022 - nature.com
Methane-oxidizing bacteria play a central role in greenhouse gas mitigation and have
potential applications in biomanufacturing. Their primary metabolic enzyme, particulate …

Structural basis of directional switching by the bacterial flagellum

S Johnson, JC Deme, EJ Furlong, JJE Caesar… - Nature …, 2024 - nature.com
The bacterial flagellum is a macromolecular protein complex that harvests energy from uni-
directional ion flow across the inner membrane to power bacterial swimming via rotation of …

Structural basis of torque generation in the bi-directional bacterial flagellar motor

H Hu, M Santiveri, N Wadhwa, HC Berg… - Trends in biochemical …, 2022 - cell.com
The flagellar stator unit is an oligomeric complex of two membrane proteins (MotA 5 B 2) that
powers bi-directional rotation of the bacterial flagellum. Harnessing the ion motive force …

Structural basis of the bacterial flagellar motor rotational switching

J Tan, L Zhang, X Zhou, S Han, Y Zhou, Y Zhu - Cell Research, 2024 - nature.com
The bacterial flagellar motor is a huge bidirectional rotary nanomachine that drives rotation
of the flagellum for bacterial motility. The cytoplasmic C ring of the flagellar motor functions …