Human health benefits of very-long-chain polyunsaturated fatty acids from microalgae

J Lupette, C Benning - Biochimie, 2020 - Elsevier
Microalgae are single-cell, photosynthetic organisms whose biodiversity places them at the
forefront of biological producers of high-value molecules including lipids and pigments …

Molecular mechanisms for biosynthesis and assembly of nutritionally important very long chain polyunsaturated fatty acids in microorganisms

X Qiu, X Xie, D Meesapyodsuk - Progress in Lipid Research, 2020 - Elsevier
Very long chain polyunsaturated fatty acids (VLCPUFAs) such as docosahexaenoic acid
(DHA, 22: 6n-3), arachidonic acid (ARA, 20: 4n-6) and eicosapentaenoic acid (EPA, 20: 5 …

Plant and algal lipidomes: Analysis, composition, and their societal significance

J Jouhet, E Alves, Y Boutté, S Darnet… - Progress in Lipid …, 2024 - Elsevier
Plants and algae play a crucial role in the earth's ecosystems. Through photosynthesis they
convert light energy into chemical energy, capture CO2 and produce oxygen and energy …

Immunomodulatory compounds from the sea: From the origins to a modern marine pharmacopoeia

EA Cutolo, R Campitiello, R Caferri, VF Pagliuca, J Li… - Marine Drugs, 2024 - mdpi.com
From sea shores to the abysses of the deep ocean, marine ecosystems have provided
humanity with valuable medicinal resources. The use of marine organisms is discussed in …

Diatom–bacteria interactions in the marine environment: complexity, heterogeneity, and potential for biotechnological applications

F Di Costanzo, V Di Dato, G Romano - Microorganisms, 2023 - mdpi.com
Diatom–bacteria interactions evolved during more than 200 million years of coexistence in
the same environment. In this time frame, they established complex and heterogeneous …

Lipid mediators in marine diatoms

I Orefice, V Di Dato, A Sardo, C Lauritano, G Romano - Aquatic Ecology, 2022 - Springer
Diatoms are eukaryotic microalgae representing one of the major groups in the marine
phytoplankton, accounting for up to 40% of annual productivity at sea. They are widely …

The Clinical Promise of Microalgae in Rheumatoid Arthritis: From Natural Compounds to Recombinant Therapeutics

EA Cutolo, R Caferri, R Campitiello, M Cutolo - Marine Drugs, 2023 - mdpi.com
Rheumatoid arthritis (RA) is an invalidating chronic autoimmune disorder characterized by
joint inflammation and progressive bone damage. Dietary intervention is an important …

Isoprostanoid profiling of marine microalgae

C Vigor, C Oger, G Reversat, A Rocher, B Zhou… - Biomolecules, 2020 - mdpi.com
Algae result from a complex evolutionary history that shapes their metabolic network. For
example, these organisms can synthesize different polyunsaturated fatty acids, such as …

Prostaglandin pathway activation in the diatom Skeletonema marinoi under grazer pressure

R Barbarinaldi, F Di Costanzo, I Orefice… - Marine Environmental …, 2024 - Elsevier
Prostaglandins (Pgs) are eicosanoid lipid mediators detected in all vertebrates, in some
marine invertebrates, macroalgae and in diatoms, a class of eukaryotic microalgae …

Janus Kinase 2/Signal Transducer and Activator of Transcription 3/Cyclooxygenase 2 Signaling Pathway Mediates the Effect of Central Angiotensin II on the Elevation …

JF Fan, X Tan, W Wang, JK Li, YC Xiao… - Journal of the …, 2024 - ahajournals.org
Background Prostaglandin E2 (PGE2) in the rostral ventrolateral medulla (RVLM) has been
recognized as a pivotal pressor substance in hypertension, yet understanding of its effects …