CD44, a nonkinase single span transmembrane glycoprotein, is a major cell surface
receptor for many other extracellular matrix components as well as classic markers of cancer …

Objectives The aim of this study was to investigate the role and molecular mechanism of
proline/arginine-rich end leucine-rich repeat protein (PRELP), a secreted protein in …

Background Heart failure (HF) and cancer share common risk factors and
pathophysiological mechanisms, including fibrosis. Identifying biomarkers and therapeutic …

Solid tumors present a formidable challenge in oncology, necessitating innovative
approaches to improve therapeutic outcomes. Proteoglycans, multifaceted molecules within …

Background Tendomodulin (TNMD) is pivotal in various malignancies, including colorectal
cancer (CRC). However, its comprehensive impact across cancers, particularly its …