[HTML][HTML] Butyrate ameliorates chronic alcoholic central nervous damage by suppressing microglia-mediated neuroinflammation and modulating the microbiome-gut …

H Wei, C Yu, C Zhang, Y Ren, L Guo, T Wang… - Biomedicine & …, 2023 - Elsevier
Background Alcohol abuse triggers neuroinflammation, leading to neuronal damage and
further memory and cognitive impairment. Few satisfactory advances have been made in the …

Subregional Differences in Alcohol Modulation of Central Amygdala Neurocircuitry

M Melkumyan, Y Silberman - Frontiers in molecular neuroscience, 2022 - frontiersin.org
Alcohol use disorder is a highly significant medical condition characterized by an impaired
ability to stop or control alcohol use, compulsive alcohol seeking behavior, and withdrawal …

The Influence of Arsenic Co-Exposure in a Model of Alcohol-Induced Neurodegeneration in C57BL/6J Mice

TR Sides, JC Nelson, KN Nwachukwu, J Boston… - Brain Sciences, 2023 - mdpi.com
Both excessive alcohol consumption and exposure to high levels of arsenic can lead to
neurodegeneration, especially in the hippocampus. Co-exposure to arsenic and alcohol can …

[HTML][HTML] Ethanol Exacerbates the Alzheimer's Disease Pathology in the 5xFAD Mouse Model

HE Mohammed, JC Nelson, SA Marshall - Neuroglia, 2024 - mdpi.com
Alzheimer's disease (AD) is the most common form of dementia with characteristic biological
markers. Clinically, AD presents as declines in memory, reasoning, and decision making …

Genetic and functional adaptations and alcohol-biased signaling in the mediodorsal thalamus of alcohol dependent mice

JC Martin, KC Reeves, KA Carter, M Davis… - bioRxiv, 2024 - biorxiv.org
Alcohol Use Disorder (AUD) is a significant health concern characterized by an individual's
inability to control alcohol intake. With alcohol misuse increasing and abstinence rates …

Early life psychosocial stress increases binge-like ethanol consumption and CSF1R inhibition prevents stress-induced alterations in microglia and brain macrophage …

SC Gironda, SW Centanni, JL Weiner - bioRxiv, 2024 - biorxiv.org
Early life stress (ELS) has lasting consequences on microglia and brain macrophage
function. During ELS, microglia and brain macrophages alter their engagement with …

Sodium butyrate alleviates chronic alcoholic neuroinflammation by regulating microgila polarization through GPR109A/PPAR-γ/NF-κB signaling pathway

H Wei, Y Ren, C Yu, C Zhang, L Guo, T Wang, F Chen… - 2022 - researchsquare.com
Background Alcohol can cause neuroinflammation, leading to neuron damage and further
memory and cognitive impairment. Recent animal studies have shown that the exposure to …