Contributions of eosinophils to human health and disease

AD Klion, SJ Ackerman… - Annual Review of …, 2020 - annualreviews.org
The human eosinophil has long been thought to favorably influence innate mucosal
immunity but at times has also been incriminated in disease pathophysiology. Research into …

Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment: sponsored by the American …

GT Furuta, CA Liacouras, MH Collins, SK Gupta… - Gastroenterology, 2007 - Elsevier
During the last decade, clinical practice saw a rapid increase of patients with esophageal
eosinophilia who were thought to have gastroesophageal reflux disease (GERD) but who …

Management guidelines of eosinophilic esophagitis in childhood

A Papadopoulou, S Koletzko… - Journal of pediatric …, 2014 - journals.lww.com
Objectives: Eosinophilic esophagitis (EoE) represents a chronic, immune/antigen-mediated
esophageal disease characterized clinically by symptoms related to esophageal dysfunction …

Common variants at 5q22 associate with pediatric eosinophilic esophagitis

ME Rothenberg, JM Spergel, JD Sherrill, K Annaiah… - Nature …, 2010 - nature.com
Eosinophilic esophagitis (EoE) is an allergic disorder characterized by the accumulation of
eosinophils in the esophagus. We report association of EoE with variants at chromosome …

Advances in clinical management of eosinophilic esophagitis

ES Dellon, CA Liacouras - Gastroenterology, 2014 - Elsevier
Eosinophilic esophagitis (EoE) is a chronic immune/antigen-mediated clinicopathologic
condition that has become an increasingly important cause of upper gastrointestinal …

IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids

C Blanchard, MK Mingler, M Vicario, JP Abonia… - Journal of Allergy and …, 2007 - Elsevier
BACKGROUND: Eosinophilic esophagitis (EE) is an emerging worldwide disease that
mimics gastroesophageal reflux disease. Early studies have established that esophageal …

Diagnostic, functional, and therapeutic roles of microRNA in allergic diseases

TX Lu, ME Rothenberg - Journal of Allergy and Clinical Immunology, 2013 - Elsevier
Allergic inflammation is accompanied by the coordinated expression of a myriad of genes
and proteins that initiate, sustain, and propagate immune responses and tissue remodeling …

Identification of specific foods responsible for inflammation in children with eosinophilic esophagitis successfully treated with empiric elimination diet

AF Kagalwalla, A Shah, BUK Li… - Journal of pediatric …, 2011 - journals.lww.com
Objectives: Eosinophilic esophagitis (EoE) is an immune-mediated chronic inflammatory
disorder triggered by food antigen (s). A 6-food elimination diet (SFED) excluding cow's milk …

Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis

C Blanchard, EM Stucke, K Burwinkel… - The Journal of …, 2010 - journals.aai.org
We have previously proposed that the pathogenesis of eosinophilic esophagitis (EE) is
mediated by an IL-13–driven epithelial cell response associated with marked gene …

Diagnosis and treatment of eosinophilic esophagitis

A Straumann, DA Katzka - Gastroenterology, 2018 - Elsevier
Eosinophilic esophagitis (EoE) is a new disease. It is caused by a T-helper type 2 cell
response to food antigens in contact with the esophageal mucosa. Although no single …