Skeletal muscle contains a designated population of adult stem cells, called satellite cells,
which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically …

Skeletal muscle has remarkable regeneration capabilities, mainly due to its resident muscle
stem cells (MuSCs). In this review, we introduce recently developed technologies and the …

Extracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which
is of great significance to tissue development. ECM in muscle fiber niche consists of three …

Muscle stem cells (MuSCs) are essential for tissue homeostasis and regeneration, but the
potential contribution of MuSC morphology to in vivo function remains unknown. Here, we …

Muscle stem cells, or satellite cells, are required for skeletal muscle maintenance, growth,
and repair. Following satellite cell activation, several factors drive asymmetric cell division to …

Volumetric muscle loss (VML) is associated with loss of skeletal muscle function, and current
treatments show limited efficacy. Here we show that bioconstructs suffused with genetically …

Many tissues harbor quiescent stem cells that are activated upon injury, subsequently
proliferating and differentiating to repair tissue damage. Mechanisms by which stem cells …

The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy
not only seriously reduces people's quality of life and increases morbidity and mortality, but …

The skeletal muscle microenvironment transiently remodels and stiffens after exercise and
injury, as muscle ages, and in myopathic muscle; however, how these changes in stiffness …

Quiescence is a cellular state in which a cell remains out of the cell cycle but retains the
capacity to divide. The unique ability of adult stem cells to maintain quiescence is crucial for …