The mechanisms of action of deep brain stimulation and ideas for the future development

K Udupa, R Chen - Progress in neurobiology, 2015 - Elsevier
Deep brain stimulation (DBS) has been used as a treatment of movement disorders such as
Parkinson's disease, dystonia, and essential tremor for over twenty years, and is a promising …

Deep brain stimulation in drug addiction treatment: research progress and perspective

R Chang, J Peng, Y Chen, H Liao, S Zhao… - Frontiers in …, 2022 - frontiersin.org
Drug addiction is a chronic psychiatric disorder characterized by compulsive drug-seeking
and drug-using behavior, and a tremendous socioeconomic burden to society. Current …

Somatic inhibition by microscopic magnetic stimulation

H Ye, L Barrett - Scientific Reports, 2021 - nature.com
Electric currents can produce quick, reversible control of neural activity. Externally applied
electric currents have been used in inhibiting certain ganglion cells in clinical practices. Via …

Contribution of decreased serotonin release to the antidyskinetic effects of deep brain stimulation in a rodent model of tardive dyskinesia: Comparison of the …

MC Creed, C Hamani, A Bridgman… - Journal of …, 2012 - Soc Neuroscience
Mechanisms whereby deep brain stimulation (DBS) of the subthalamic nucleus (STN) or
internal globus pallidus (GPi) reduces dyskinesias remain largely unknown. Using vacuous …

Cellular mechanisms underlying state-dependent neural inhibition with magnetic stimulation

H Ye, V Chen, J Hendee - Scientific Reports, 2022 - nature.com
Novel stimulation protocols for neuromodulation with magnetic fields are explored in clinical
and laboratory settings. Recent evidence suggests that the activation state of the nervous …

Chronically Implanted Microelectrodes Cause c-fos Expression Along Their Trajectory

P Pflüger, RC Pinnell, N Martini… - Frontiers in …, 2020 - frontiersin.org
When designing electrodes and probes for brain–machine interfaces, one of the challenges
faced involves minimizing the brain-tissue response, which would otherwise create an …

High frequency stimulation of subthalamic nucleus results in behavioral recovery by increasing striatal dopamine release in 6-hydroxydopamine lesioned rat

Z He, Y Jiang, H Xu, H Jiang, W Jia, P Sun… - Behavioural brain …, 2014 - Elsevier
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective medical
therapy in alleviating motor symptoms in moderate to severe Parkinson's disease (PD) …

[HTML][HTML] Neuromodulation with electromagnetic stimulation for seizure suppression: from electrode to magnetic coil

H Ye, S Kaszuba - IBRO reports, 2019 - Elsevier
Non-invasive brain tissue stimulation with a magnetic coil provides several irreplaceable
advantages over that with an implanted electrode, in altering neural activities under …

High‐frequency electrical stimulation suppresses cholinergic accumbens interneurons in acute rat brain slices through GABAB receptors

Y Xie, T Heida, J Stegenga, Y Zhao… - European journal of …, 2014 - Wiley Online Library
The nucleus accumbens is selected as a surgical target in deep brain stimulation for treating
refractory obsessive‐compulsive disorder (OCD). One of the therapeutic benefits of this …

Focal suppression of epileptiform activity in the hippocampus by a high-frequency magnetic field

H Ye, VCF Chen, J Helon, N Apostolopoulos - Neuroscience, 2020 - Elsevier
Electric current has been used for epilepsy treatment by targeting specific neural circuitries.
Despite its success, direct contact between the electrode and tissue could cause side effects …