Recent advances in DNA origami-engineered nanomaterials and applications

P Zhan, A Peil, Q Jiang, D Wang, S Mousavi… - Chemical …, 2023 - ACS Publications
DNA nanotechnology is a unique field, where physics, chemistry, biology, mathematics,
engineering, and materials science can elegantly converge. Since the original proposal of …

Unraveling and overcoming platinum drug‐resistant cancer tumors with DNA nanostructures

Y Yu, L Zhang, Z Qin, J Karges… - Advanced Functional …, 2023 - Wiley Online Library
Abstract All chemotherapeutic treatments worldwide (> 50%) use platinum‐based
compounds. Despite their clinical success, an increasing number of platinum drug‐resistant …

Applications of terminal deoxynucleotidyl transferase enzyme in biotechnology

J Ashley, IM Potts, FJ Olorunniji - ChemBioChem, 2023 - Wiley Online Library
The use of polymerase enzymes in biotechnology has allowed us to gain unprecedented
control over the manipulation of DNA, opening up new and exciting applications in areas …

Spatial-and valence-matched neutralizing DNA nanostructure blocks wild-type SARS-CoV-2 and omicron variant infection

S Wan, S Liu, M Sun, J Zhang, X Wei, T Song, Y Li… - ACS …, 2022 - ACS Publications
Natural ligand–receptor interactions that play pivotal roles in biological events are ideal
models for design and assembly of artificial recognition molecules. Herein, aiming at the …

Enzymatic synthesis of TNA protects DNA nanostructures

B Qin, Q Wang, Y Wang, F Han, H Wang… - Angewandte Chemie …, 2024 - Wiley Online Library
Xeno‐nucleic acids (XNAs) are synthetic genetic polymers with improved biological
stabilities and offer powerful molecular tools such as aptamers and catalysts. However, XNA …

Controlling Silicification on DNA Origami with Polynucleotide Brushes

S Wang, PA Lin, M DeLuca, S Zauscher… - Journal of the …, 2023 - ACS Publications
DNA origami has been used as biotemplates for growing a range of inorganic materials to
create novel organic–inorganic hybrid nanomaterials. Recently, the solution-based …

Prediction and control in DNA nanotechnology

M DeLuca, S Sensale, PA Lin, G Arya - ACS applied bio materials, 2023 - ACS Publications
DNA nanotechnology is a rapidly developing field that uses DNA as a building material for
nanoscale structures. Key to the field's development has been the ability to accurately …

[HTML][HTML] Synthetic intrinsically disordered protein fusion tags that enhance protein solubility

NC Tang, JC Su, Y Shmidov, G Kelly… - Nature …, 2024 - nature.com
We report the de novo design of small (< 20 kDa) and highly soluble synthetic intrinsically
disordered proteins (SynIDPs) that confer solubility to a fusion partner with minimal effect on …

NucleoCraft: the art of Stimuli-Responsive Precision in DNA and RNA bioengineering

L Yu, L Chen, D Satyabola, A Prasad, H Yan - BME frontiers, 2024 - spj.science.org
Recent advancements in DNA and RNA bioengineering have paved the way for developing
stimuli-responsive nanostructures with remarkable potential across various applications …

Spatiotemporal Control over Polynucleotide Brush Growth on DNA Origami Nanostructures

Y Yang, Q Lu, Y Chen, M DeLuca… - Angewandte Chemie …, 2023 - Wiley Online Library
DNA nanotechnology provides an approach to create precise, tunable, and biocompatible
nanostructures for biomedical applications. However, the stability of these structures is …