Objective The mechanisms of chondrocytes ferroptosis in osteoarthritis (OA) have not yet
been fully elucidated. This study aimed to identify key ferroptosis related genes (FRGs) …

Osteoarthritis (OA) is a progressive degenerative disorder impacting bones and joints,
worsened by chronic inflammation, immune dysregulation, mechanical stress, metabolic …

Colon cancer contributes to high mortality rates internationally that has seriously
endangered human health. Aurora kinase A (AURKA) served as a key molecule in colon …

Background: Inflammatory breast cancer (IBC) is a rare and poorly characterized type of
breast cancer with an aggressive clinical presentation. The biological mechanisms driving …

Background: Invasive ductal carcinoma (IDC) is the most common type of breast cancer (BC)
worldwide. Nowadays, due to its heterogeneity and high capacity for metastasis, it is …

Inflammatory breast cancer (IBC) is a rare and aggressive form of breast cancer. This thesis
investigates the potential of a computational drug repurposing approach coupled with in …