Delirium in critical illness: clinical manifestations, outcomes, and management

JL Stollings, K Kotfis, G Chanques, BT Pun… - Intensive care …, 2021 - Springer
Delirium is the most common manifestation of brain dysfunction in critically ill patients. In the
intensive care unit (ICU), duration of delirium is independently predictive of excess death …

Antipsychotics for treating delirium in hospitalized adults: a systematic review

R Nikooie, KJ Neufeld, ES Oh, LM Wilson… - Annals of Internal …, 2019 - acpjournals.org
Background: Delirium is common in hospitalized patients and is associated with worse
outcomes. Antipsychotics are commonly used; however, the associated benefits and harms …

[HTML][HTML] Haloperidol for the treatment of delirium in ICU patients

NC Andersen-Ranberg, LM Poulsen… - … England Journal of …, 2022 - Mass Medical Soc
Background Haloperidol is frequently used to treat delirium in patients in the intensive care
unit (ICU), but evidence of its effect is limited. Methods In this multicenter, blinded, placebo …

Ebola virus disease

D Malvy, AK McElroy, H de Clerck, S Günther… - The Lancet, 2019 - thelancet.com
Ebolaviruses are pathogenic agents associated with a severe, potentially fatal, systemic
disease in man and great apes. Four species of ebolaviruses have been identified in west or …

Distribution of delirium motor subtypes in the intensive care unit: a systematic scoping review

KN la Cour, NC Andersen-Ranberg, S Weihe… - Critical care, 2022 - Springer
Background Delirium is the most common cerebral dysfunction in the intensive care unit
(ICU) and can be subdivided into a hypoactive, hyperactive, or mixed motor subtype based …

Safety and efficacy of dexmedetomidine in acutely ill adults requiring noninvasive ventilation: a systematic review and meta-analysis of randomized trials

K Lewis, J Piticaru, D Chaudhuri, J Basmaji, E Fan… - Chest, 2021 - Elsevier
Background Although clinical studies have evaluated dexmedetomidine as a strategy to
improve noninvasive ventilation (NIV) comfort and tolerance in patients with acute …

Early mobilisation for prevention and treatment of delirium in critically ill patients: systematic review and meta-analysis

P Nydahl, MM Jeitziner, V Vater, S Sivarajah… - Intensive and Critical …, 2023 - Elsevier
Objective Does early mobilisation as standalone or part of a bundle intervention, compared
to usual care, prevent and/or shorten delirium in adult patients in Intensive Care Units …

The effectiveness of non-pharmacological interventions in reducing the incidence and duration of delirium in critically ill patients: a systematic review and meta …

L Bannon, J McGaughey, R Verghis, M Clarke… - Intensive Care …, 2019 - Springer
Purpose To evaluate the effect of non-pharmacological interventions versus standard care
on incidence and duration of delirium in critically ill patients. Methods We searched …

Long-term outcomes with haloperidol versus placebo in acutely admitted adult ICU patients with delirium

CB Mortensen, NC Andersen-Ranberg… - Intensive Care …, 2024 - Springer
Purpose We assessed long-term outcomes in acutely admitted adult patients with delirium
treated in intensive care unit (ICU) with haloperidol versus placebo. Methods We conducted …

Delirium in intensive care

LM Poulsen, S Estrup, CB Mortensen… - Current anesthesiology …, 2021 - Springer
Abstract Purpose of Review Delirium in the intensive care unit (ICU) has become
increasingly acknowledged as a significant problem for critically ill patients affecting both the …