[HTML][HTML] Polymer bioconjugates: Modern design concepts toward precision hybrid materials

C Chen, DYW Ng, T Weil - Progress in Polymer Science, 2020 - Elsevier
The conjugation of synthetic polymers with various biomolecules provides an easy access to
biohybrid materials which combine advantages from both the synthetic world and Nature …

[HTML][HTML] Cyclobutenyl macromonomers: Synthetic strategies and ring-opening metathesis polymerization

D Le, G Morandi, S Legoupy, S Pascual… - European polymer …, 2013 - Elsevier
In contrast to their (oxa) norbornenyl counterparts, cyclobutenyl derivatives have remained
relatively unexplored in ring-opening metathesis polymerization (ROMP), despite ROMP of …

Understanding the Biological Interactions of pH‐Swellable Nanoparticles

SS Kermaniyan, M Chen, C Zhang… - Macromolecular …, 2022 - Wiley Online Library
Abstract pH‐responsive nanoparticles have generated significant interest for use as drug
delivery systems due to their potential for inducible release at low pH. The pH variation from …

Protein–polymer conjugates synthesized using water-soluble azlactone-functionalized polymers enable receptor-specific cellular uptake toward targeted drug delivery

JS Kim, AR Sirois, AJ Vazquez Cegla… - Bioconjugate …, 2019 - ACS Publications
Conjugation of proteins to drug-loaded polymeric structures is an attractive strategy for
facilitating target-specific drug delivery for a variety of clinical needs. Polymers currently …

Soft Matter Nanoparticles with Reactive Coronal Pentafluorophenyl Methacrylate Residues via Non‐Polar RAFT Dispersion Polymerization and Polymerization …

Y Pei, JM Noy, PJ Roth, AB Lowe - Journal of Polymer Science …, 2015 - Wiley Online Library
Soft matter nanoparticles exhibiting rich polymorphism with reactive pentafluorophenyl
methacrylate (PFPMA) units in their coronae were prepared via non‐polar reversible …

Thermoresponsive (Co) polymers through Postpolymerization Modification of Poly (2-vinyl-4, 4-dimethylazlactone)

Y Zhu, JY Quek, AB Lowe, PJ Roth - Macromolecules, 2013 - ACS Publications
Poly (2-vinyl-4, 4-dimethylazlactone), pVDMA, is emerging as a versatile reactive platform in
polymer chemistry. Herein, postpolymerization modification of pVDMA leading to …

Poly (2-isopropenyl-2-oxazoline)–a structural analogue to poly (vinyl azlactone) with Orthogonal Reactivity

MN Leiske, AM Mahmoud, NM Warne, JACM Goos… - Polymer …, 2020 - pubs.rsc.org
In this study, we report a straightforward method to orthogonally functionalise (co) polymers
of two independently addressable reactive monomers–the structural analogues 2 …

Azlactone-based heterobifunctional linkers with orthogonal clickable groups: efficient tools for bioconjugation with complete atom economy

A Bénard, G Forcher, M Le Bohec… - Organic & …, 2018 - pubs.rsc.org
We report the efficient synthesis of a series of new azlactone-based heterofunctional linkers
bearing two orthogonal clickable groups that proceed with full atom economy. These new …

RAFT Synthesis and aqueous solution behavior of novel pH-and thermo-responsive (co) polymers derived from reactive poly (2-vinyl-4, 4-dimethylazlactone) scaffolds

JY Quek, Y Zhu, PJ Roth, TP Davis, AB Lowe - Macromolecules, 2013 - ACS Publications
Well-defined homopolymers of 2-vinyl-4, 4-dimethylazlactone (VDA) and AB diblock
copolymers of VDA with N, N-dimethylacrylamide (DMA) and N-isopropylacrylamide …

Selective postmodification of copolymer backbones bearing different activated esters with disparate reactivities

Y Li, HTT Duong, MW Jones, JS Basuki, J Hu… - ACS Macro …, 2013 - ACS Publications
In this communication, we report an easy method for introducing functional groups into
polymer structures by successively reacting two different activated ester functionalities …