Mechanisms of cancer pain
R Haroun, JN Wood, S Sikandar - Frontiers in Pain Research, 2023 - frontiersin.org
Personalised and targeted interventions have revolutionised cancer treatment and
dramatically improved survival rates in recent decades. Nonetheless, effective pain …
dramatically improved survival rates in recent decades. Nonetheless, effective pain …
Unlocking the potential of TRPV1 based siRNA therapeutics for the treatment of chemotherapy-induced neuropathic pain
Chemotherapy-induced neuropathic pain (CINP) is among the most common clinical
complications associated with the use of anti-cancer drugs. CINP occurs in nearly 68.1% of …
complications associated with the use of anti-cancer drugs. CINP occurs in nearly 68.1% of …
Neural circuit mechanisms of sensorimotor disability in cancer treatment
SN Housley, P Nardelli… - Proceedings of the …, 2021 - National Acad Sciences
Cancer survivors rank sensorimotor disability among the most distressing, long-term
consequences of chemotherapy. Disorders in gait, balance, and skilled movements are …
consequences of chemotherapy. Disorders in gait, balance, and skilled movements are …
Wearables, sensors, and smart devices for the detection and monitoring of chemotherapy‐induced peripheral neurotoxicity: Systematic review and directions for future …
Chemotherapy‐induced peripheral neurotoxicity (CIPN) diagnosis is largely based on
patient reported outcomes. Wearables, sensors, and smart devices may potentially provide …
patient reported outcomes. Wearables, sensors, and smart devices may potentially provide …
Cancer survivors post-chemotherapy exhibit unimpaired short-latency stretch reflexes in the proximal upper extremity
AB Wang, SN Housley, D Ludvig… - Journal of …, 2023 - journals.physiology.org
Oxaliplatin (OX) chemotherapy can lead to long-term sensorimotor impairments in cancer
survivors. The impairments are often thought to be caused by OX-induced progressive …
survivors. The impairments are often thought to be caused by OX-induced progressive …
Identification of novel neuroprotectants against vincristine-induced neurotoxicity in iPSC-derived neurons
V Petrova, AR Snavely, J Splaine, S Zhen… - Cellular and Molecular …, 2024 - Springer
Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling side effect of cancer
chemotherapy that can often limit treatment options for cancer patients or have life-long …
chemotherapy that can often limit treatment options for cancer patients or have life-long …
Endoplasmic reticulum stress in chemotherapy-induced peripheral neuropathy: Emerging role of phytochemicals
Chemotherapy-induced peripheral neuropathy (CIPN) is a significant dose-limiting long-
term sequela in cancer patients undergoing treatment, often leading to discontinuation of …
term sequela in cancer patients undergoing treatment, often leading to discontinuation of …
Mechanosensory encoding dysfunction emerges from cancer-chemotherapy interaction
Persistent sensory, motor and cognitive disabilities comprise chemotherapy-induced neural
disorders (CIND) that limit quality of life with little therapeutic relief for cancer survivors. Our …
disorders (CIND) that limit quality of life with little therapeutic relief for cancer survivors. Our …
Cancer survivors post-chemotherapy exhibit unique proprioceptive deficits in proximal limbs
AB Wang, SN Housley, AM Flores, TC Cope… - … of neuroengineering and …, 2022 - Springer
Background Oxaliplatin (OX) chemotherapy for colorectal cancer is associated with adverse
neurotoxic effects that can contribute to long-term sensorimotor impairments in cancer …
neurotoxic effects that can contribute to long-term sensorimotor impairments in cancer …
Secondary parkinsonism associated with focal brain lesions
Focal imaging abnormalities in patients with parkinsonism suggest secondary etiology and
require a distinctive clinical approach to diagnosis and treatment. We review different …
require a distinctive clinical approach to diagnosis and treatment. We review different …