Miniaturized liquid chromatography focusing on analytical columns and mass spectrometry: A review

EVS Maciel, AL de Toffoli, E Sobieski, CED Nazário… - Analytica chimica …, 2020 - Elsevier
The technological advances achieved over the last decades boosted the development of
suitable benchtop platforms to work at miniaturized liquid chromatography scale (capillary …

Portable mass spectrometry system: instrumentation, applications, and path to 'omics analysis

J Wang, ME Pursell, A DeVor, O Awoyemi… - …, 2022 - Wiley Online Library
Mass spectrometry (MS) is an information rich analytical technique and plays a key role in
various 'omics studies. Standard mass spectrometers are bulky and operate at high vacuum …

Facile improvement of negative ion mode electrospray ionization using capillary vibrating sharp-edge spray ionization

C Li, K Attanayake, SJ Valentine, P Li - Analytical chemistry, 2020 - ACS Publications
Electrospray ionization (ESI) is often affected by corona discharge when spraying 100%
aqueous solutions as the voltage that induces discharge can be well below the onset …

In‐droplet hydrogen–deuterium exchange to examine protein/peptide solution conformer heterogeneity

D Sharif, M Rahman, S Mahmud… - Rapid …, 2023 - Wiley Online Library
Rationale Many different structure analysis techniques are not capable of probing the
heterogeneity of solution conformations. Here, we examine the ability of in‐droplet hydrogen …

Synthesis of tunable gold nanostars via 3D-printed microfluidic device with vibrating sharp-tip acoustic mixing

K Curtin, T Godary, P Li - Microfluidics and Nanofluidics, 2023 - Springer
Gold nanostars are valuable materials for nanomedicine, energy conversation, and
catalysis. Microfluidic synthesis offers a simple and controlled means to produce …

Characterizing Multidevice Capillary Vibrating Sharp-Edge Spray Ionization for In-Droplet Hydrogen/Deuterium Exchange to Enhance Compound Identification

A DeBastiani, SN Majuta, D Sharif, K Attanayake… - ACS …, 2021 - ACS Publications
Multidevice capillary vibrating sharp-edge spray ionization (cVSSI) source parameters have
been examined to determine their effects on conducting in-droplet hydrogen/deuterium …

Hydrogen/deuterium exchange for the analysis of carbohydrates

JB Hatvany, ES Gallagher - Carbohydrate research, 2023 - Elsevier
Carbohydrates and glycans are integral to many biological processes, including cell-cell
recognition and energy storage. However, carbohydrates are often difficult to analyze due to …

Capillary vibrating sharp-edge spray ionization augments field-free ionization techniques to promote conformer preservation in the gas-phase for intractable …

D Sharif, SH Foroushani, K Attanayake… - The Journal of …, 2022 - ACS Publications
Field-free capillary vibrating sharp-edge spray ionization (cVSSI) is evaluated for its ability to
conduct native mass spectrometry (MS) experiments. The charge state distributions for nine …

Charge within Nt17 peptides modulates huntingtin aggregation and initial lipid binding events

AR Stonebraker, R Hankin, KL Kapp, P Li… - Biophysical …, 2023 - Elsevier
Toxic aggregation of pathogenic huntingtin protein (htt) is implicated in Huntington's disease
and influenced by various factors, including the first seventeen amino acids at the N …

Combining Field-Enabled Capillary Vibrating Sharp-Edge Spray Ionization with Microflow Liquid Chromatography and Mass Spectrometry to Enhance 'Omics …

SN Majuta, A DeBastiani, P Li… - Journal of the American …, 2021 - ACS Publications
Field-enabled capillary vibrating sharp-edge spray ionization (cVSSI) has been combined
with high-flow liquid chromatography (LC) and mass spectrometry (MS) to establish current …