Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

Mounting evidence has indicated microRNA (miR) dysregulation and the Wnt/β-catenin
signaling pathway jointly drive carcinogenesis, cancer metastasis, and drug-resistance. The …

Long non-coding RNAs (lncRNAs) are involved in the pathology of various tumors, including
colorectal cancer (CRC). The crosstalk between carcinoma-associated fibroblasts (CAFs) …

Worldwide, breast cancer (BC) is the most common malignancy in women, in regard to
incidence and mortality. In recent years, the negative role of obesity during BC development …

Studies over the past four decades have elucidated the role of Wnt/β-catenin mediated
regulation in cell proliferation, differentiation and migration. These processes are …

Drug resistance is a major problem in the treatment of cancer patients. Resistance can
develop after prolonged cycles of chemotherapy or can be present intrinsically in the patient …

MicroRNAs (miRNAs) are involved in virtually all biological processes, including stem cell
maintenance, differentiation, and development. The dysregulation of miRNAs is associated …

HOTAIR (HOX transcript antisense RNA) plays a critical role in chromatin dynamics through
the interaction with histone modifiers resulting in transcriptional gene silencing. The …

Objective The aim of this study was to explore the expression and biological role of miR-370-
3p in human gliomas. Methods Clinical specimens from the brains of 20 glioma patients and …

Breast cancer is one of the most commonly diagnosed cancer types worldwide. Regarding
molecular characteristics and classification, it is a heterogeneous disease, which makes it …