RNA medicines represent a paradigm shift in treatment and prevention of critical diseases of
global significance, eg, infectious diseases. The highly successful messenger RNA (mRNA) …

Despite the recent advances in drug development, the majority of novel therapeutics have
not been successfully translated into clinical applications. One of the major factors hindering …

Chimeric antigen receptor T cell (CAR-T cell) therapy has shown impressive success in the
treatment of hematological malignancies, but the systemic toxicity and complex …

Mesoporous silica nanoparticles (MSNPs) are a particular example of innovative
nanomaterials for the development of drug delivery systems. MSNPs have recently received …

Mutant p53 proteins result from missense mutations in the TP53 gene, the most mutated in
human cancer, and have been described to contribute to cancer initiation and progression …

In this work, the novel bioink composed of alginate and polyethyleneimine were prepared
with different concentrations of alginate and polyethyleneimine (PEI) and used to measure …

Mesoporous silica nanoparticles (MSNs) find tremendous applications in drug delivery due
to several advantages such as their easy fabrication process, high drug loading …

Introduction Most lung diseases are serious conditions resulting from genetic and
environmental causes associated with high mortality and severe symptoms. Currently …

Diamond and carbon nanostructures possess outstanding advantages, such as chemical
inertness, stable fluorescence, tunable surface characteristics and excellent biocompatibility …

Acute liver injury (ALI) is one of the most important causes of liver failure, and there are no
FDA-approved drugs that could therapy late-stage ALI. It has been shown in this study that …