Microbiota–gut–brain axis and epilepsy: a review on mechanisms and potential therapeutics

M Ding, Y Lang, H Shu, J Shao, L Cui - Frontiers in Immunology, 2021 - frontiersin.org
The gut–brain axis refers to the bidirectional communication between the gut and brain, and
regulates intestinal homeostasis and the central nervous system via neural networks and …

The microbiota–microglia axis in central nervous system disorders

O Mossad, D Erny - Brain Pathology, 2020 - Wiley Online Library
The innate immune system in the central nervous system (CNS) is mainly represented by
specialized tissue‐resident macrophages, called microglia. In the past years, various …

Repetitive restricted behaviors in autism spectrum disorder: From mechanism to development of therapeutics

J Tian, X Gao, L Yang - Frontiers in neuroscience, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by deficits in social communication, social interaction, and repetitive restricted behaviors …

Targeting the microbiome-gut-brain axis for improving cognition in schizophrenia and major mood disorders: A narrative review

M Bioque, A González-Rodríguez… - Progress in Neuro …, 2021 - Elsevier
Cognitive impairment has been consistently found to be a core feature of serious mental
illnesses such as schizophrenia and major mood disorders (major depression and bipolar …

Microbiota gut–brain axis in ischemic stroke: a narrative review with a focus about the relationship with inflammatory bowel disease

E Sinagra, G Pellegatta, V Guarnotta, M Maida, F Rossi… - Life, 2021 - mdpi.com
The gut microbiota is emerging as an important player in neurodevelopment and aging as
well as in brain diseases including stroke, Alzheimer's disease, and Parkinson's disease …

The microbiome–gut–brain axis in epilepsy: pharmacotherapeutic target from bench evidence for potential bedside applications

S Kundu, S Nayak, D Rakshit, T Singh… - European Journal of …, 2023 - Wiley Online Library
The gut–brain axis augments the bidirectional communication between the gut and brain
and modulates gut homeostasis and the central nervous system through the hypothalamic …

Local protein translation and RNA processing of synaptic proteins in autism spectrum disorder

Y Joo, DR Benavides - International Journal of Molecular Sciences, 2021 - mdpi.com
Autism spectrum disorder (ASD) is a heritable neurodevelopmental condition associated
with impairments in social interaction, communication and repetitive behaviors. While the …

Melatonin improves learning and memory of mice with chronic social isolation stress via an interaction between microglia polarization and BDNF/TrkB/CREB signaling …

S Bagheri, K Moradi, E Ehghaghi, A Badripour… - European Journal of …, 2021 - Elsevier
Chronic social isolation stress (SIS) could impair learning and memory-related behaviors.
Herein, we investigated the efficacy of Melatonin in treatment of memory despair and also its …

Autism, heparan sulfate and potential interventions

J Alexander, G Keles, J Killingsworth, R Bronson… - Experimental …, 2022 - Elsevier
Developmental disabilities are defined as disorders that result in the limitation of function
due to impaired development of the nervous system; these disabilities can be present in the …

Selective probiotic treatment positively modulates the microbiota–gut–brain Axis in the BTBR mouse model of autism

A Pochakom, C Mu, JM Rho, TA Tompkins… - Brain Sciences, 2022 - mdpi.com
Recent studies have shown promise for the use of probiotics in modulating behaviour
through the microbiota–gut–brain axis. In the present study, we assessed the impact of two …