Osteosarcoma is a malignant bone tumor characterized by the direct production of osteoid
tissue from tumor cells. Extracellular vesicles are membranous vesicles released by cells …

Schistosomes are long lived, intravascular parasitic platyhelminths that infect> 200 million
people globally. The molecular mechanisms used by these blood flukes to dampen host …

Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …

Human schistosomiasis is caused by helminths of the genus Schistosoma. Macrophages
play a crucial role in the immune regulation of this disease. These cells acquire different …

MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression being
involved in many different biological processes and play a key role in developmental timing …

Bone sarcomas are rare cancers accompanied by metastatic disease, mainly including
osteosarcoma, Ewing sarcoma and chondrosarcoma. Extracellular vesicles (EVs) are …

The co-evolution of Schistosoma and its host necessitates the use of extracellular vesicles
(EVs) generated by different lifecycle stages to manipulate the host immune system to …

Clonorchis sinensis is closely associated with cholangitis, cholecystitis, biliary fibrosis and
cholangiocarcinoma. The present study elucidated the role of extracellular vesicles of C …

Schistosomiasis is a fatal zoonotic parasitic disease that also threatens human health. The
main pathological features of schistosomiasis are granulomatous inflammation and …

Following their first interaction with the antigen, quiescent naive T-helper (Th; CD4+) cells
enlarge, differentiate, and proliferate; these processes are accompanied by substantial …