Access to effective affordable contraception is critical for individual and public health. A wide
range of hormonal contraceptives (HCs), which differ in composition, concentration of the …

Depression and posttraumatic stress disorder increase the risk of idiopathic preterm birth
(iPTB); however, the exact molecular mechanism is unknown. Depression and stress-related …

Ovarian sex steroids can modulate new vessel formation and development, and the
clarification of the underlying mechanism will provide insight into neovascularization-related …

Vertical transmission of the Zika virus (ZIKV) causes severe fetal defects, but the exact
pathogenic mechanism is unclear. We identified up to a 10,480-fold higher expression of …

Background Today, androgen receptor (AR)-mediated signaling mechanisms in prostate
cancer are intensively studied. However, the roles of other steroid hormones in prostate …

SARS-CoV-2 infects cells via binding to ACE2 and TMPRSS2, which allows the virus to fuse
with host cells. The viral RNA is detected in the placenta of SARS-CoV-2-infected pregnant …

Defective decidualization of human endometrial stromal cells (ESCs) has recently been
highlighted as an underlying cause of implantation failure. FK-506-binding protein 51 …

To evaluate gene expression associated with unfavorable vaginal bleeding in users of the
Etonogestrel (ENG) contraceptive implant. Prospective study involving 100 women who …

Progestin-only long-acting reversible-contraceptive (pLARC)-exposed endometria displays
decidualized human endometrial stromal cells (HESCs) and hyperdilated thin-walled fragile …

Introduction The contraceptive activity of synthetic progestins is mediated through three
basic mechanisms:(a) An anti-gonadotrophic action leading to the inhibition of ovulation;(b) …