The process of altering neural activity–neuromodulation–has long been used to treat
patients with brain disorders and answer scientific questions. Deep brain stimulation in …

Deep brain stimulation (DBS) has advanced treatment options for a variety of neurologic and
neuropsychiatric conditions. As the technology for DBS continues to progress, treatment …

Deep brain stimulation (DBS) is a highly efficacious treatment option for movement disorders
and a growing number of other indications are investigated in clinical trials. To ensure …

The human thalamus is a brain structure that comprises numerous, highly specific nuclei.
Since these nuclei are known to have different functions and to be connected to different …

Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …

The study of the hypothalamus and its topological changes provides valuable insights into
underlying physiological and pathological processes. Owing to technological limitations …

Essential tremor is the most prevalent movement disorder and is often refractory to medical
treatment. Deep brain stimulation offers a therapeutic approach that can efficiently control …

At the group-level, deep brain stimulation leads to significant therapeutic benefit in a
multitude of neurological and neuropsychiatric disorders. At the single-patient level …

Neuroimaging has seen a paradigm shift away from a formal description of local activity
patterns towards studying distributed brain networks. The recently defined framework of the …

The pathophysiology of dystonic tremor and essential tremor remains partially understood.
In patients with medication-refractory dystonic tremor or essential tremor, deep brain …