Autophagy causes the breakdown of damaged proteins and organelles to their constituent
components. The phosphatidylinositol 3‐kinase (PI3K) pathway played an important role in …

Immunotherapy is currently the most rapidly advancing area of clinical oncology, and
provides the unprecedented opportunity to effectively treat, and even cure, several …

Abstract NF-E2-related factor 2 (Nrf2) protein is a basic-region leucine zipper transcription
factor that defends against endogenous or exogenous stressors. By inducing several …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

ABSTRACT SQSTM1 (also known as p62) is a multifunctional stress-inducible scaffold
protein involved in diverse cellular processes. Its functions are tightly regulated through an …

p62 is a stress‐inducible protein able to change among binding partners, cellular
localizations and form liquid droplet structures in a context‐dependent manner. This protein …

Over the past few years, the field of regulated cell death continues to expand and novel
mechanisms that orchestrate multiple regulated cell death pathways are being unveiled …

Sequestosome1 (p62/SQSTM 1) is a multidomain protein that interacts with the autophagy
machinery as a key adaptor of target cargo. It interacts with phagophores through the LC3 …

Background Eukaryotic cells demonstrate two tightly linked vesicular transport systems,
comprising intracellular vesicle transport and extracellular vesicle transport system …

Objective To investigate the impact of death-associated protein kinase 1 (Dapk1) on
lipopolysaccharide (LPS)-induced acute lung injury (ALI) via p38MAPK/NF-κB pathway …