Revisiting the oxidation of flavonoids: Loss, conservation or enhancement of their antioxidant properties

H Speisky, F Shahidi, A Costa de Camargo, J Fuentes - Antioxidants, 2022 - mdpi.com
Flavonoids display a broad range of health-promoting bioactivities. Among these, their
capacity to act as antioxidants has remained most prominent. The canonical reactive oxygen …

Flavonoids: classification, function, and molecular mechanisms involved in bone remodelling

P Ramesh, R Jagadeesan, S Sekaran… - Frontiers in …, 2021 - frontiersin.org
Flavonoids are polyphenolic compounds spotted in various fruits, vegetables, barks, tea
plants, and stems and many more natural commodities. They have a multitude of …

Antioxidant and anti-inflammatory activities of quercetin and its derivatives

M Lesjak, I Beara, N Simin, D Pintać, T Majkić… - Journal of Functional …, 2018 - Elsevier
Quercetin is hardly bioavailable and largely transformed to different metabolites. Although
little is known about their biological activities, these metabolites are crucial for explanation of …

Quercetin as an agent for protecting the bone: a review of the current evidence

SK Wong, KY Chin, S Ima-Nirwana - International journal of molecular …, 2020 - mdpi.com
Quercetin is a flavonoid abundantly found in fruits and vegetables. It possesses a wide
spectrum of biological activities, thus suggesting a role in disease prevention and health …

[HTML][HTML] New perspectives on the therapeutic potential of quercetin in non-communicable diseases: Targeting Nrf2 to counteract oxidative stress and inflammation

L Zhang, LY Xu, F Tang, D Liu, XL Zhao… - Journal of …, 2024 - Elsevier
Abstract Non-communicable diseases (NCDs), including cardiovascular diseases, cancer,
metabolic diseases, and skeletal diseases, pose significant challenges to public health …

Theoretical study of the antioxidant activity of quercetin oxidation products

A Vásquez-Espinal, O Yañez, E Osorio… - Frontiers in …, 2019 - frontiersin.org
It was recently shown that, when tested in cellular systems, quercetin oxidized products
(Qox) have significantly better antioxidant activity than quercetin (Q) itself. The main Qox …

RETRACTED: Quercetin improve ischemia/reperfusion‐induced cardiomyocyte apoptosis in vitro and in vivo study via SIRT1/PGC‐1α signaling

J Tang, L Lu, Y Liu, J Ma, L Yang, L Li… - Journal of Cellular …, 2019 - Wiley Online Library
Aim To evaluate the effects of quercetin to improve ischemia/reperfusion‐induced
cardiomyocyte apoptosis in vitro and in vivo study. Methods The cells were divided into five …

Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed)

IA Schepetkin, AG Ramstead, LN Kirpotina… - Phytotherapy …, 2016 - Wiley Online Library
Epilobium angustifolium is a medicinal plant used around the world in traditional medicine
for the treatment of many disorders and ailments. Experimental studies have demonstrated …

The flavonoid quercetin inhibits titanium dioxide (TiO2)-induced chronic arthritis in mice

SM Borghi, SS Mizokami, FA Pinho-Ribeiro… - The Journal of …, 2018 - Elsevier
Titanium dioxide (TiO 2) is a common component of orthopedic prosthesis. However,
prosthesis wear releases TiO 2, which induces inflammation and osteolysis in peri-prosthetic …

Quercetin oxidation paradoxically enhances its antioxidant and cytoprotective properties

J Fuentes, E Atala, E Pastene… - Journal of agricultural …, 2017 - ACS Publications
Quercetin oxidation is generally believed to ultimately result in the loss of its antioxidant
properties. To test this assertion, quercetin oxidation was induced, and after each of its major …