Neural stem cells in the adult mammalian brain are the source of new neurons that
contribute to complex sensory and cognitive functions. Most adult neural stem cells are …

Of wide interest for health is the relation existing between depression, a very common
psychological illness, accompanied by anxiety and reduced ability to concentrate, and adult …

Although the neurogenesis-enhancing effects of exercise have been extensively studied, the
molecular mechanisms underlying this response remain unclear. Here, we propose that this …

Background In recent years, much evidence has emerged to indicate that exercise can
benefit people when performed properly. This review summarizes the exercise interventions …

Hypoxic damage to the developing brain due to preterm birth causes many anatomical
changes, including damage to the periventricular white matter. This results in the loss of glial …

Alzheimer's disease (AD) is characterized by severe neuronal loss as well as the
accumulation of amyloid‐β (Aβ), which ultimately leads to plaque formation. Although there …

Physical activity is a strong positive physiological modulator of adult neurogenesis in the
hippocampal dentate gyrus. Although the underlying regulatory mechanisms are still …

Cellular redox states regulate the balance between stem cell maintenance and activation.
Increased levels of intracellular reactive oxygen species (ROS) are linked to proliferation …

Adult hippocampal neurogenesis is important for preserving learning and memory‐related
cognitive functions. Physical exercise, especially voluntary running, is one of the strongest …

This paper bridges critical gaps through proposing a novel, environmentally mediated brain-
derived neurotrophic factor (BDNF)-interactive model that promises to sustain adult …