NJ Short, D Nguyen, F Ravandi - Blood cancer journal, 2023 - nature.com
FLT3 is the most frequently mutated gene in acute myeloid leukemia (AML), with FLT3 internal tandem duplication (ITD) mutations being associated with a more aggressive clinical …
VA Guerra, C DiNardo, M Konopleva - Best practice & research Clinical …, 2019 - Elsevier
The prognosis of adult acute myeloid leukemia (AML) remains poor, with the long-term survival rate less than 50%. However, the current paradigms of treatment are changing …
NG Daver, P Vyas, S Kambhampati… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Magrolimab is a first-in-class humanized monoclonal antibody against cluster of differentiation 47, an antiphagocytic signal used by cancer cells to evade phagocytosis …
M Norouzi, M Amerian, M Amerian, F Atyabi - Drug discovery today, 2020 - Elsevier
Cancer incidence and mortality are rapidly growing worldwide. In attempts to develop more efficacious therapeutic regimens for patients with cancer, nanomedicines have found …
HA Hou, HF Tien - Journal of biomedical science, 2020 - Springer
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy in terms of clinical features, underlying pathogenesis and treatment outcomes. Recent advances in …
G Nagel, D Weber, E Fromm, S Erhardt, M Lübbert… - Annals of …, 2017 - Springer
We describe genetic and clinical characteristics of acute myeloid leukemia (AML) patients according to age from an academic population-based registry. Adult patients with newly …
AK Eisfeld, J Kohlschmidt, A Mims, D Nicolet… - Leukemia, 2020 - nature.com
Abstract The European LeukemiaNet (ELN) recommendations for diagnosis and management of acute myeloid leukemia (AML) have become an important tool to assess …
H Döhner, A Dolnik, L Tang, JF Seymour, MD Minden… - Leukemia, 2018 - nature.com
Older patients with newly diagnosed acute myeloid leukemia (AML) in the phase 3 AZA-AML- 001 study were evaluated at entry for cytogenetic abnormalities, and a subgroup of patients …
C Récher, C Röllig, E Bérard, S Bertoli, PY Dumas… - Leukemia, 2022 - nature.com
The outcome of acute myeloid leukemia patients aged 70 years or older is poor. Defining the best treatment option remains controversial especially when choosing between intensive …