The teleology of sex differences has been argued since at least as early as Aristotle's
controversial Generation of Animals more than 300 years BC, which reflects the sex bias of …

The beneficial effects of n-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) on human
health are widely known. Humans are rather inefficient in synthesizing n-3 LC-PUFA; thus …

Hypertension is a frequent condition encountered during kidney disease development and a
leading cause in its progression. Hallmark factors contributing to hypertension constitute a …

This review article provides an update for the role of prostaglandin E2 receptors (EP1, EP2,
EP3 and EP4) in cardiovascular disease. Where possible we have reported citations from …

This review article summarizes the role of prostaglandin E 2 (PGE 2) and its receptors (EP1-
EP4) as it relates to the inflammatory cardiomyopathy, myocarditis. During the COVID-19 …

Nutrient imbalances during gestation are a risk factor for hypertension in offspring. Although
the effects of prenatal nutritional deficiency on the development of hypertension and …

Human hypertension caused by in-frame deletion of CULLIN3 exon-9 (Cul3∆ 9) is driven by
renal and vascular mechanisms. We bred conditionally activatable Cul3∆ 9 transgenic mice …

Vascular dysfunction induced by angiotensin-II can result from direct effects on vascular and
inflammatory cells and indirect hemodynamic effects. Using isolated and functional cultured …

Rationale: Arterial remodeling serves as a pivotal mechanism underlying the development
of diseases such as hypertension. Fibulin-7 (FBLN7), an adhesion protein, remains …

Excess sodium consumption contributes to arterial dysfunction in humans. The C57BL/6
strain of mice has been used to identify mechanisms by which arterial dysfunction occurs …