2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: Developed by the task force for the diagnosis and treatment of pulmonary …

M Humbert, G Kovacs, MM Hoeper… - European heart …, 2022 - academic.oup.com
Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and may be associated with a variety of cardiovascular and respiratory …

The evolving landscape of pulmonary arterial hypertension clinical trials

J Weatherald, A Boucly, A Peters, D Montani, K Prasad… - The Lancet, 2022 - thelancet.com
Although it is a rare disease, the number of available therapeutic options for treating
pulmonary arterial hypertension has increased since the late 1990s, with multiple drugs …

[HTML][HTML] Phase 3 trial of sotatercept for treatment of pulmonary arterial hypertension

MM Hoeper, DB Badesch, HA Ghofrani… - … England Journal of …, 2023 - Mass Medical Soc
Background Pulmonary arterial hypertension is a progressive disease involving proliferative
remodeling of the pulmonary vessels. Despite therapeutic advances, the disease-associated …

[HTML][HTML] 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

M Humbert, G Kovacs, MM Hoeper… - European …, 2022 - publications.ersnet.org
2022 ESC/ERS pulmonary hypertension guidelines incorporate changes and adaptations
focusing on clinical management https://bit. ly/3QtUvb4

Treatment of pulmonary arterial hypertension: recent progress and a look to the future

M Humbert, O Sitbon, C Guignabert… - The Lancet …, 2023 - thelancet.com
Pulmonary arterial hypertension (PAH) is a severe but treatable form of pre-capillary
pulmonary hypertension caused by pulmonary vascular remodelling. As a result of basic …

Phenotypes in pulmonary hypertension

J Weatherald, AR Hemnes, BA Maron… - European …, 2024 - publications.ersnet.org
The clinical classification of pulmonary hypertension (PH) has guided diagnosis and
treatment of patients with PH for several decades. Discoveries relating to underlying …

Predictors of outcomes in mild pulmonary hypertension according to 2022 ESC/ERS Guidelines: the EVIDENCE-PAH UK study

N Karia, L Howard, M Johnson, DG Kiely… - European Heart …, 2023 - academic.oup.com
Abstract Background and Aims Interventional studies in pulmonary arterial hypertension
completed to date have shown to be effective in symptomatic patients with significantly …

Evolving concepts in endothelial pathobiology of pulmonary arterial hypertension

ND Cober, MM VandenBroek, ML Ormiston… - …, 2022 - Am Heart Assoc
Pulmonary arterial hypertension (PAH) is a deadly disease, characterized by increased
vascular resistance, pulmonary arteriolar loss, and occlusive arterial remodeling, leading to …

Improved survival for patients with systemic sclerosis–associated pulmonary arterial hypertension: the Johns Hopkins Registry

HJ Hassan, M Naranjo, N Ayoub, T Housten… - American journal of …, 2023 - atsjournals.org
Rationale: To date, it remains unclear whether recent changes in the management of
patients with systemic sclerosis–associated pulmonary hypertension (SSc-PH) have …

Initial combination therapy with macitentan and tadalafil in patients with pulmonary arterial hypertension, with and without cardiac comorbidities

VV McLaughlin, O Sitbon, KM Chin… - European journal of …, 2024 - Wiley Online Library
Aims According to current guidelines, initial monotherapy should be considered for
pulmonary arterial hypertension (PAH) patients with cardiopulmonary comorbidities. This …