Transcription factors serve critical roles in the progressive development of general body
plan, organ commitment, and finally, specific cell types. It has been the hope of most …

▪ Abstract Many organs including the mammalian lung and vascular system consist of
branched tubular networks that transport essential gases or fluids, but the genetic programs …

Identifying the genomic changes that control morphological variation and understanding
how they generate diversity is a major goal of evolutionary biology. In Heliconius butterflies …

The positioning and elaboration of ectodermal veins in the wing of Drosophila melanogaster
rely on widely utilized developmental signals, including those mediated by EGF, BMP …

Branching morphogenesis involves the restructuring of epithelial tissues into complex and
organized ramified tubular networks. Early rounds of branching are controlled genetically in …

The veins are cuticular structures that differentiate in precise patterns in insect wings. The
genetic and molecular basis of vein pattern formation in Drosophila melanogaster is …

The characterisation of ligands that activate the JAK/STAT pathway has the potential to
throw light onto a comparatively poorly understood aspect of this important signal …

The veins in the Drosophila wing have a characteristic width, which is regulated by the
activity of the Notch pathway. The expression of the Notch-ligand Delta is restricted to the …

The dynamics of extracellular signal-regulated kinase (ERK) signaling underlies its versatile
functions in cell differentiation, cell proliferation, and cell motility. Classical studies in …

Background The vast diversity in morphology of insect wings provides an excellent model to
study morphological evolution. The best-described wing modification is the specification of …