Diagnosis and management of Graves disease: a global overview

L Bartalena - Nature Reviews Endocrinology, 2013 - nature.com
Graves disease is an autoimmune disorder characterized by goitre, hyperthyroidism and, in
25% of patients, Graves ophthalmopathy. The hyperthyroidism is caused by thyroid …

Pretibial myxedema: pathophysiology and treatment options

V Fatourechi - American journal of clinical dermatology, 2005 - Springer
Pretibial myxedema or localized myxedema or thyroid dermopathy is an autoimmune
manifestation of Graves' disease. It also occasionally occurs in Hashimoto's thyroiditis …

Thyroid dermopathy and acropachy

V Fatourechi - Graves' Disease: A Comprehensive Guide for …, 2015 - Springer
Thyroid dermopathy that occurs in 4–13% of patients with Graves' ophthalmopathy is an
extrathyroidal manifestation of Graves' disease. Thyroid acropachy commonly presents with …

Diagnosis and treatment of Graves disease

DD Streetman, U Khanderia - Annals of Pharmacotherapy, 2003 - journals.sagepub.com
OBJECTIVE: To review the etiology, diagnosis, and clinical presentation of Graves disease
and provide an overview of the standard and adjunctive treatments. Specifically, antithyroid …

Prevention of Graves' ophthalmopathy

L Bartalena - Best Practice & Research Clinical Endocrinology & …, 2012 - Elsevier
Smoking is the most important risk factor for the occurrence/progression of Graves'
ophthalmopathy (GO), as well as for its lower/slower response to immunosuppression …

Effects of Total Thyroid Ablation Versus Near-Total Thyroidectomy Alone on Mild to Moderate Graves' Orbitopathy Treated with Intravenous Glucocorticoids

F Menconi, M Marinò, A Pinchera… - The Journal of …, 2007 - academic.oup.com
Abstract Context: Graves' orbitopathy (GO) is probably caused by autoimmune reactions
against autoantigen (s) shared by thyroid and orbital tissues sustained by intrathyroidal …

The dilemma of how to manage Graves' hyperthyroidism in patients with associated orbitopathy

L Bartalena - The Journal of Clinical Endocrinology & …, 2011 - academic.oup.com
Context: Graves' orbitopathy (GO) is present in about 50% of patients with Graves'
hyperthyroidism. It may range from mild to moderately severe and (rarely) to sight …

Adalimumab as steroid-sparing treatment of inflammatory-stage thyroid eye disease

R Ayabe, DB Rootman, CJ Hwang… - Ophthalmic Plastic & …, 2014 - journals.lww.com
Purpose: Steroids are often used as medical therapy for active thyroid eye disease (TED).
While high-dose steroids have been shown to be effective in reducing the severity of TED …

Management of Graves' ophthalmopathy

WM Wiersinga - Nature Clinical Practice Endocrinology & Metabolism, 2007 - nature.com
Management of Graves' ophthalmopathy is preferably done in a multidisciplinary setting.
Smoking is associated with worse disease outcome. 131I therapy for hyperthyroidism can …

Time course of Graves' ophthalmopathy after total thyroidectomy alone or followed by radioiodine therapy: a 2-year longitudinal study

A De Bellis, G Conzo, G Cennamo, E Pane… - Endocrine, 2012 - Springer
The findings in hyperthyroid patients with Graves' orbitopathy (GO) of antibodies against
antigens shared between the thyroid and orbit, such as the TSH-receptor (TRAb) and a …